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Uploader: Martin Golebiewski
Contributor: Andreas Hoppe, Christian Bölling, Nicolas Le Novère
Other contributors: Not specified
Model type: Not specified
Model format: SBML
Version: 1
Projects: A: Cellular level, HepatoSys, Virtual Liver
Organism: Homo sapiens
Environment: Not specified
Scales: Cell
Multiple models of human metabolism have been reconstructed, but each represents only a subset of our knowledge. Here we describe Recon 2, a community-driven, consensus 'metabolic reconstruction', which is the most comprehensive representation of human metabolism that is applicable to computational modeling. Compared with its predecessors, the reconstruction has improved topological and functional features, including ∼2× more reactions and ∼1.7× more unique metabolites. Using Recon 2 we predicted
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Created: 27th Nov 2013 at 10:35
ViewUploader: Bernd Binder
Contributor: Bernd Binder, Hermann-Georg Holzhütter, Nikolaus Berndt
Other contributors: Not specified
Model type: Ordinary differential equations (ODE)
Model format: Not specified
Scales: Cell
Formation, degradation and renewal of cellular organelles is a dynamic process based on permanent budding, fusion and inter-organelle traffic of vesicles.
Created: 30th Jan 2014 at 11:07 Last updated: 30th Jan 2014 at 11:07
Download Uploader: Iryna Ilkavets
Contributor: Andreas Hecht
Other contributors: Not specified
Model type: Ordinary differential equations (ODE)
Model format: PDF (Model description)
Version: 1
Projects: A2.5: Integration of insulin and Wnt signalling in hepatocytes, B2.2: Importance of Wnt- and Hedgehog factors for hepatic stellate cells...
Organism: Not specified
Environment: Not specified
Scales: Cell
It is a link to a supplementary information from a publication: Benary, U., Kofahl, B., Hecht, A. and Wolf, J. (2015), Mathematical modelling suggests a differential impact of β-transducin repeat-containing protein paralogues on Wnt/β-catenin signalling dynamics. FEBS Journal, 282: 1080–1096. doi: 10.1111/febs.13204
http://onlinelibrary.wiley.com/doi/10.1111/febs.13204/suppinfo
The Wnt/β-catenin signalling pathway is involved in the regulation of a multitude of cellular processes by controlling
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Created: 15th Jun 2015 at 13:22 Last updated: 15th Jun 2015 at 14:19
Uploader: Bernd Binder
Contributor: Bernd Binder
Other contributors: Not specified
Model type: Ordinary differential equations (ODE)
Model format: Not specified
Scales: Not specified
Rabs constitute a group of small GTPases that confer directionality to intracellular vesicle transport by promoting on the membrane of transport vesicles in the formation of specific protein complexes allowing for efficient fusion with a selected set of target organelles. The molecular mechanism controlling recruitment of the correct Rab at the right time is not fully understood. We propose a model according to which the residence time of a given Rab on the membrane of an organelle is determined
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Created: 30th Jan 2014 at 11:17 Last updated: 30th Jan 2014 at 11:17
Uploader: Data From HepatoSys
Contributor: Data From HepatoSys, Reinhard Guthke, Rolf Gebhardt, Sebastian Zellmer, Wolfgang Schmidt-Heck
Other contributors: H. Buentemeyer, D. Teupser, J. Thiery
Model type: Not specified
Model format: SBML
Scales: Cell
amino acid metabolism of cultured mouse hepatocytes
Created: 25th Jul 2011 at 15:09 Last updated: 24th Feb 2012 at 15:26
