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Uploader: Lutz Brusch
Contributor: Andreas Deutsch, Anja Voß–Böhme, Nadine Hohmann, Olaf Dirsch, Uta Dahmen, Weiwei Wei
Other contributors: Not specified
Model type: Not specified
Model format: Not specified
Version: 1
Projects: C2: Organization of the sinusoidal system and the liver lobule - referen..., C6: Organization and function of the sinusoidal system and the liver lob..., D4: Regeneration and Liver Size
Organism: Not specified
Environment: Not specified
Scales: Liver lobule and Liver
Model has been published in Hohmann et al., PLoS ONE 9(4): e93207 (2014), doi: 10.1371/journal.pone.0093207
Created: 24th Jan 2014 at 14:33 Last updated: 17th Jun 2014 at 11:42
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Download Uploader: Markus Krauß
Contributor: Jörg Lippert, Lars Küpfer, Markus Krauß
Other contributors: Not specified
Model type: Ordinary differential equations (ODE)
Model format: SXML
Version: 1
Projects: E4: Vertical integration across biological scales, E: Model integration
Organism: Homo sapiens
Environment: MoBi
Scales: Organism
Mobi PBPK Models of Paracetamol, Ammonia and Allopurinol, relating to Publication Krauss et al (2012) in PLoS Comp Biol
Created: 30th Oct 2012 at 09:09 Last updated: 6th May 2015 at 08:07
Uploader: Sascha Bulik
Contributor: Hermann-Georg Holzhütter, Nikolaus Berndt, Sascha Bulik
Other contributors: Not specified
Model type: Ordinary differential equations (ODE)
Model format: Not specified
Scales: Cell
The model comprises the reactions of the citric acid cycle, the respiratory chain, oxidative phosphorylation, mitochondrial ATP generation, the exchange of adenine nucleotides exchange between mitochondrial matrix and cytosol, as well as the transport of small ions across the inner mitochondrial membrane.
The respiratory chain complexes I and III are modelled in high resolution providing insight into electron occupation states of ROS generating sites depending on energetic challenge and enzyme
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Created: 5th Nov 2012 at 09:45 Last updated: 5th Nov 2012 at 09:45
Uploader: Lutz Brusch
Contributor: Lutz Brusch
Other contributors: Not specified
Model type: Ordinary differential equations (ODE)
Model format: Not specified
Version: 1
Projects: A3.2: Cross-talk of signaling pathways and endocytic machinery in hepato...
Organism: Not specified
Environment: Not specified
Scales: Cell
Morpheus model of Smo regulation in response to Hh
As used in refereence:
A.P. Kupinski, I. Raabe, M. Michel, D. Ail, L. Brusch, T. Weidemann, C. Bökel (2013) Phosphorylation of the Smo tail is controlled by membrane localization and is dispensable for clustering, J. Cell Sci., 126, 20, 4684-4697 doi: 10.1242/jcs.128926
Created: 28th Jan 2014 at 10:17 Last updated: 28th Jan 2014 at 10:18
Uploader: Walter De Back
Contributor: Andreas Deutsch, Lutz Brusch, Walter De Back
Other contributors: Not specified
Model type: Not specified
Model format: Not specified
Version: 2
Projects: A3.2: Cross-talk of signaling pathways and endocytic machinery in hepato..., A3.3: Hepatocyte polarity, A3.5: The impact of cell polarity on metabolism detoxification and endoc..., B2.3: Effect of hepatic stellate cells on hepatocyte polarity and transd..., B3: Intercellular communication through cell adhesion, B: Communication of Hepatocytes and Non-Parenchymal Liver Cells, C2: Organization of the sinusoidal system and the liver lobule - referen..., C5: Structural changes and functional consequences of the liver lobular/..., C6: Organization and function of the sinusoidal system and the liver lob..., C: Liver lobule level, D4: Regeneration and Liver Size, E2: Integration on the liver lobule scale: Image processing and mathemat..., E3: Horizontal integration on organ scale, E: Model integration
Organism: Not specified
Environment: Not specified
Scales: Cell, Intercellular and Liver lobule
Morpheus is the modeling environment for multicellular systems biology developed at the IMC group (prof. Andreas Deutsch) at the Center for High Performance Computing at the the Technische Universität Dresden.
Created: 23rd Oct 2012 at 13:08 Last updated: 4th Dec 2012 at 13:35
Uploader: Data From HepatoSys
Contributor: Data From HepatoSys, Reinhard Guthke, Rolf Gebhardt, Sebastian Zellmer, Wolfgang Schmidt-Heck
Other contributors: Not specified
Model type: Not specified
Model format: SBML
Scales: Cell
Aminosäure-Abbau in primären Maushepatozyten
Created: 1st Aug 2011 at 12:16 Last updated: 24th Feb 2012 at 15:25
