Publications
Authors: K. Meyer, O. Ostrenko, G. Bourantas, H. Morales-Navarrete, N. Porat-Shliom, F. Segovia-Miranda, H. Nonaka, A. Ghaemi, J. M. Verbavatz, L. Brusch, I. Sbalzarini, Y. Kalaidzidis, R. Weigert, M. Zerial
PubMed ID: 28330614
Date Published: 24th Mar 2017
Projects: Showcase LIAM (Liver Image Analysis Based Model)
Journal: Cell Syst
Citation: Cell Syst. 2017 Mar 15. pii: S2405-4712(17)30052-2. doi: 10.1016/j.cels.2017.02.008.
Scales: Liver lobule
Abstract (Expand)
Created: 25th Jul 2017 at 13:19
Activating and Inhibitory Functions of WNT/β-catenin in the Induction of Cytochromes P450 by Nuclear Receptors in HepaRG Cells
Authors: Maria Thomas, Christine Bayha, Silvia Vetter, Ute Hofmann, Michael Schwarz, Ulrich M Zanger, Albert Braeuning
PubMed ID: 25824487
Date Published: 1st Apr 2015
Projects: A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes, Showcase Steatosis
Journal: Mol. Pharmacol.
Citation: Mol. Pharmacol. :
Authors: Aidan Budd, Manuel Corpas, Michelle D. Brazas, Jonathan C. Fuller, Jeremy Goecks, Nicola J. Mulder, Magali Michaut, B. F. Francis Ouellette, Aleksandra Pawlik, Niklas Blomberg
DOI: 10.1371/journal.pcbi.1003972
Date Published: 5th Feb 2015
Projects: No Projects
Journal: PLoS Comput Biol
Citation: PLoS Comput Biol 11(2) : e1003972
Scales: Not specified
Abstract (Expand)
Created: 9th Feb 2015 at 13:55 Last updated: 9th Feb 2015 at 14:06
A Systematic Comparison of the Impact of Inflammatory Signaling on ADME Gene Expression and Activity in Primary Human Hepatocytes and HepaRG Cells
Authors: Marcus Klein, Maria Thomas, Ute Hofmann, Daniel Seehofer, Georg Damm, Ulrich M Zanger
PubMed ID: 25480923
Date Published: 7th Dec 2014
Projects: A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes, Showcase LPS and Inflammation, Showcase Steatosis
Journal: Drug Metab. Dispos.
Citation: Drug Metab. Dispos. :
Scales: Not specified
Abstract (Expand)
Created: 7th Dec 2014 at 10:17
Authors: Lars Ole Schwen, Weiwei Wei, Felix Gremse, Josef Ehling, Lei Wang, Uta Dahmen, Tobias Preusser
DOI: 10.1016/j.jtbi.2014.10.026
Date Published: 1st Nov 2014
Projects: D1: Regulation of Blood Flow and Perfusion in the Liver, E3: Horizontal integration on organ scale, E4: Vertical integration across biological scales
Journal: Journal of Theoretical Biology
Citation: Journal of Theoretical Biology
Scales: Liver
Abstract (Expand)
Created: 17th Nov 2014 at 10:07 Last updated: 17th Nov 2014 at 10:12
Adenoviral overexpression of Lhx2 attenuates cell viability but does not preserve the stem cell like phenotype of hepatic stellate cells
Authors: Berit Genz, Maria Thomas, Brigitte M Pützer, Marcin Siatkowski, Georg Fuellen, Brigitte Vollmar, Kerstin Abshagen
PubMed ID: 24995995
Date Published: 6th Jul 2014
Projects: A: Cellular level, B: Communication of Hepatocytes and Non-Parenchymal Liver Cells
Journal: Exp. Cell Res.
Citation: Exp. Cell Res. :
A model integration approach linking signalling and gene-regulatory logic with kinetic metabolic models
Authors: A. Ryll, J. Bucher, A. Bonin, S. Bongard, E. Gonçalves, J. Saez-Rodriguez, J. Niklas, S. Klamt
DOI: 10.1016/j.biosystems.2014.07.002
Date Published: 1st Jul 2014
Projects: A1: Cellular metabolism, A2.5: Integration of insulin and Wnt signalling in hepatocytes, A2: Integration of Signalling Pathways in Hepatocellular Response, A3.4: Linking signalling to metabolic functions, A3.6: Transcription factor network and links to metabolism in NAFLD, A: Cellular level, Showcase Steatosis, Virtual Liver
Journal: Biosystems
Citation: Biosystems
Scales: Cell
Abstract (Expand)
Created: 6th Aug 2014 at 07:36 Last updated: 6th Aug 2014 at 07:50
A testing strategy to predict risk for drug-induced liver injury in humans using high-content screen assays and the 'rule-of-two' model
Authors: Minjun Chen, Chun-Wei Tung, Qiang Shi, Lei Guo, Leming Shi, Hong Fang, Jürgen Borlak, Weida Tong
PubMed ID: 24958025
Date Published: 11th Jun 2014
Projects: A1.2: Detoxification in hepatocytes challenged by steatotic conditions
Journal: Arch. Toxicol.
Citation: Arch. Toxicol. 88(7): 1439-49
A Novel Mitochondrial MAVS/Caspase-8 Platform Links RNA Virus-Induced Innate Antiviral Signaling to Bax/Bak-Independent Apoptosis
Authors: Souhayla El Maadidi, Laura Faletti, Birgit Berg, Christin Wenzl, Katrin Wieland, Zhijian J Chen, Ulrich Maurer, Christoph Borner
PubMed ID: 24391214
Date Published: 3rd Jan 2014
Projects: No Projects
Journal: J. Immunol.
Citation: J. Immunol. 192(3): 1171-83
Scales: Not specified
Abstract (Expand)
Created: 22nd Jan 2014 at 15:15
A multi-scale model of hepcidin promoter regulation reveals factors controlling systemic iron homeostasis
Authors: Guillem Casanovas, Anashua Banerji, Flavia d'Alessio, Martina U Muckenthaler, Stefan Legewie
PubMed ID: 24391488
Date Published: 2nd Jan 2014
Projects: B1.3: Linking modulation of iron metabolism with the impact of macrophag...
Journal: PLoS Comput. Biol.
Citation: PLoS Comput. Biol. 10(1): e1003421
A fat option for the pig: Hepatocytic differentiated mesenchymal stem cells for translational research
Authors: Sandra Brückner, Hans-Michael Tautenhahn, Sandra Winkler, Peggy Stock, Matthias Dollinger, Bruno Christ
PubMed ID: 24200501
Date Published: 4th Nov 2013
Projects: C6: Organization and function of the sinusoidal system and the liver lob..., Showcase Steatosis
Journal: Exp. Cell Res.
Citation: Exp. Cell Res. 321(2): 267-75
Authors: Tarek Magdy, Rudolf Arlanov, Stefan Winter, Thomas Lang, Kathrin Klein, Yu Toyoda, Toshihisa Ishikawa, Matthias Schwab, Ulrich M Zanger
PubMed ID: 24024896
Date Published: 13th Sep 2013
Projects: A3.4: Linking signalling to metabolic functions, G1: Clinical Translation to Invasively Characterized Patients, G2: Clinical Translation to Non-Invasive Volunteer Setting, G3: Clinical Translation to Pharmaceutical Drug Development, G4: Whole-Body Detoxification in Mouse Models
Journal: Pharmacogenomics
Citation: Pharmacogenomics 14(12): 1433-48
Scales: Not specified
Abstract (Expand)
Created: 8th Jan 2014 at 14:01
A theoretical study of lipid accumulation in the liver-implications for nonalcoholic fatty liver disease
Authors: J Schleicher, R Guthke, U Dahmen, O Dirsch, H G Holzhuetter, S Schuster
PubMed ID: 23999488
Date Published: 4th Sep 2013
Projects: A3.6: Transcription factor network and links to metabolism in NAFLD
Journal: Biochim. Biophys. Acta
Citation: Biochim. Biophys. Acta 1841(1): 62-69
Scales: Cell
Abstract (Expand)
Created: 23rd Oct 2013 at 14:55 Last updated: 24th Oct 2013 at 16:14
Assessment of hepatic detoxification activity: proposal of an improved variant of the (13)c-methacetin breath test
Authors: Hermann-Georg Holzhütter, Johan Friso Lock, Pouria Taheri, Sascha Bulik, Andrean Goede, Martin Stockmann
PubMed ID: 23967104
Date Published: 15th Aug 2013
Projects: A1.2: Detoxification in hepatocytes challenged by steatotic conditions, E4: Vertical integration across biological scales
Journal: PLoS ONE
Citation: PLoS ONE 8(8): e70780
Scales: Not specified
Abstract (Expand)
Created: 9th Sep 2013 at 15:13 Last updated: 24th Oct 2013 at 16:14
Authors: A Geissler, F Haun, D O Frank, K Wieland, M M Simon, M Idzko, R J Davis, U Maurer, C Borner
PubMed ID: 23832115
Date Published: 5th Jul 2013
Projects: No Projects
Journal: Cell Death Differ.
Citation: Cell Death Differ. 20(10): 1317-29
Scales: Not specified
Abstract (Expand)
Created: 22nd Jan 2014 at 15:18
Authors: Anne Gaebler, Robin Milan, Leon Straub, Dominik Hoelper, Lars Kuerschner, Christoph Thiele
PubMed ID: 23709689
Date Published: 23rd May 2013
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...
Journal: J. Lipid Res.
Citation: J. Lipid Res. 54(8): 2282-90
Scales: Not specified
Abstract (Expand)
Created: 6th Jan 2014 at 11:19
Authors: Philip Stegmaier, Alexander Kel, Edgar Wingender, Jürgen Borlak
DOI: 10.1371/journal.pcbi.1002958
Date Published: 21st Mar 2013
Projects: A3.6: Transcription factor network and links to metabolism in NAFLD
Journal: PLoS Comput Biol
Citation: PLoS Comput Biol 9(3) : e1002958
Scales: Cell
Abstract (Expand)
Created: 28th Mar 2013 at 11:59 Last updated: 24th Oct 2013 at 16:14
Authors: Ines Thiele, Neil Swainston, Ronan M T Fleming, Andreas Hoppe, Swagatika Sahoo, Maike K Aurich, Hulda Haraldsdottir, Monica L Mo, Ottar Rolfsson, Miranda D Stobbe, Stefan G Thorleifsson, Rasmus Agren, Christian Bölling, Sergio Bordel, Arvind K Chavali, Paul Dobson, Warwick B Dunn, Lukas Endler, David Hala, Michael Hucka, Duncan Hull, Daniel Jameson, Neema Jamshidi, Jon J Jonsson, Nick Juty, Sarah Keating, Intawat Nookaew, Nicolas Le Novère, Naglis Malys, Alexander Mazein, Jason A Papin, Nathan D Price, Evgeni Selkov, Martin I Sigurdsson, Evangelos Simeonidis, Nikolaus Sonnenschein, Kieran Smallbone, Anatoly Sorokin, Johannes H G M van Beek, Dieter Weichart, Igor Goryanin, Jens Nielsen, Hans V Westerhoff, Douglas B Kell, Pedro Mendes, Bernhard Ø Palsson
PubMed ID: 23455439
Date Published: 3rd Mar 2013
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal..., A1.2: Detoxification in hepatocytes challenged by steatotic conditions, A1.3: Identification of crucial metabolic processes during hepatocyte pr...
Journal: Nat. Biotechnol.
Citation: Nat. Biotechnol. 31(5): 419-25
Scales: Not specified
Abstract (Expand)
Created: 19th Mar 2013 at 12:53 Last updated: 24th Oct 2013 at 16:15
Abnormal body iron distribution and erythropoiesis in a novel mouse model with inducible gain of iron regulatory protein (IRP)-1 function
Authors: D Casarrubea, L Viatte, T Hallas, A Vasanthakumar, R S Eisenstein, K Schümann, M W Hentze, B Galy
PubMed ID: 23455710
Date Published: 1st Mar 2013
Projects: B1.3: Linking modulation of iron metabolism with the impact of macrophag...
Journal: J. Mol. Med.
Citation: J. Mol. Med. 91(7): 871-81
Scales: Not specified
Abstract (Expand)
Created: 14th Jan 2014 at 14:40
A Unifying Ontology to Integrate Histological and Clinical Observations for Drug-Induced Liver Injury
Authors: Yuping Wang, Zhi Lin, Zhichao Liu, Stephen Harris, Reagan Kelly, Jie Zhang, Weigong Ge, Minjun Chen, Jürgen Borlak, Weida Tong
PubMed ID: 23395088
Date Published: 12th Feb 2013
Projects: A1.2: Detoxification in hepatocytes challenged by steatotic conditions
Journal: Am. J. Pathol.
Citation: Am. J. Pathol. 182(4): 1180-7
Scales: Liver
Abstract (Expand)
Created: 5th Mar 2013 at 16:36 Last updated: 24th Oct 2013 at 16:15
A multi-scale modeling framework for individualized, spatiotemporal prediction of drug effects and toxicological risk
Authors: Juan G Diaz Ochoa, Joachim Bucher, Alexandre R R Péry, José M Zaldivar Comenges, Jens Niklas, Klaus Mauch
PubMed ID: 23346056
Date Published: 22nd Jan 2013
Projects: No Projects
Journal: Front Pharmacol
Citation: Front Pharmacol 3: 204
Scales: Not specified
Abstract (Expand)
Created: 4th Feb 2013 at 11:46 Last updated: 24th Oct 2013 at 16:15
Authors: J Lippert, M Brosch, O von Kampen, M Meyer, H.-U Siegmund, C Schafmayer, T Becker, B Laffert, L Goerlitz, S Schreiber, PJ Neuvonen, M Niemi, J Hampe, L Kuepfer
DOI: 10.1038/psp.2012.22
Date Published: 2013
Projects: G3: Clinical Translation to Pharmaceutical Drug Development, G: Clinical translation
Journal: CPT: pharmacomet. syst. pharmacol.
Citation: CPT: pharmacomet. syst. pharmacol. 2(1) : e21
Scales: Not specified
Abstract:
Created: 28th Jan 2013 at 09:55 Last updated: 24th Oct 2013 at 16:15
Authors: Federico Pinna, Sven Sahle, Katharina Beuke, Michaela Bissinger, Selcan Tuncay, Lorenz A D'Alessandro, Ralph Gauges, Andreas Raue, Jens Timmer, Ursula Klingmüller, Peter Schirmacher, Ursula Kummer, Kai Breuhahn
PubMed ID: 23293603
Date Published: 31st Dec 2012
Projects: A2.1: Multi-level regulation of signalling pathways important for primin..., A2.4: Linking signalling pathways regulating liver regeneration and orga..., B1.2: Reciprocal effect of cell-cell communication on information proces...
Journal: Front Physiol
Citation: Front Physiol 3: 466
Scales: Cell and Intercellular
Abstract (Expand)
Created: 16th Jan 2013 at 08:49 Last updated: 24th Oct 2013 at 16:15
Authors: Ignazio Garaguso, Juergen Borlak
PubMed ID: 23166814
Date Published: 15th Nov 2012
Scales: Not specified
Abstract (Expand)
Created: 14th Dec 2012 at 19:18 Last updated: 24th Oct 2013 at 16:15
Authors: Daniel Kaschek, Jens Timmer
PubMed ID: 22892133
Date Published: 14th Aug 2012
Projects: A2: Integration of Signalling Pathways in Hepatocellular Response
Journal: BMC Syst Biol
Citation: BMC Syst Biol 6: 99
Scales: Cell
Abstract (Expand)
Created: 29th Oct 2012 at 10:50 Last updated: 24th Oct 2013 at 16:16
A General Theoretical Framework to Infer Endosomal Network Dynamics from Quantitative Image Analysis
Authors: Lionel Foret, Jonathan E. Dawson, Roberto Villaseñor, Claudio Collinet, Andreas Deutsch, Lutz Brusch, Marino Zerial, Yannis Kalaidzidis, Frank Jülicher
DOI: 10.1016/j.cub.2012.06.021
Date Published: 1st Aug 2012
Projects: A3.2: Cross-talk of signaling pathways and endocytic machinery in hepato..., A3.5: The impact of cell polarity on metabolism detoxification and endoc...
Journal: Current Biology
Citation: Current Biology 22(15) : 1381
Scales: Intercellular
Abstract (Expand)
Created: 21st Sep 2012 at 14:35 Last updated: 24th Oct 2013 at 16:16
Analysis of drug metabolism activities in a miniaturized liver cell bioreactor for use in pharmacological studies
Authors: Stefan A Hoffmann, Ursula Müller-Vieira, Klaus Biemel, Daniel Knobeloch, Sandra Heydel, Marc Lübberstedt, Andreas K Nüssler, Tommy B Andersson, Jörg C Gerlach, Katrin Zeilinger
PubMed ID: 22688505
Date Published: 13th Jun 2012
Projects: C2: Organization of the sinusoidal system and the liver lobule - referen...
Journal: Biotechnology and bioengineering
Citation: Biotechnol. Bioeng. 109(12): 3172-81
Scales: Intercellular
Abstract (Expand)
Created: 24th Aug 2012 at 11:07 Last updated: 24th Oct 2013 at 16:16
An integrative model links multiple inputs and signaling pathways to the onset of DNA synthesis in hepatocytes
Authors: Jérémy Huard, Stephanie Mueller, Ernst D Gilles, Ursula Klingmüller, Steffen Klamt
PubMed ID: 22443451
Date Published: 27th Mar 2012
Projects: A2.3: Cross-talk and distinct properties of growth factor signalling reg..., E1: Integration on the cellular level
Journal: The FEBS journal
Citation: FEBS J. 279(18): 3290-313
Scales: Intercellular
Abstract (Expand)
Created: 18th Jul 2012 at 09:45 Last updated: 24th Oct 2013 at 16:16
Authors: Bernd Binder, Hermann-Georg Holzhütter
PubMed ID: 22328341
Date Published: 14th Feb 2012
Projects: A3.3: Hepatocyte polarity, A3.5: The impact of cell polarity on metabolism detoxification and endoc...
Journal: Cell Biochem. Biophys.
Citation: Cell Biochem. Biophys. 63(1): 59-71
Scales: Cell
Abstract (Expand)
Created: 18th Jul 2012 at 13:01 Last updated: 24th Oct 2013 at 16:16
A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins
Authors: Katrin Luckert, Taranjit S Gujral, Marina Chan, Mark Sevecka, Thomas O Joos, Peter K Sorger, Gavin Macbeath, Oliver Pötz
PubMed ID: 22234610
Date Published: 12th Jan 2012
Scales: Not specified
Abstract (Expand)
Created: 27th Nov 2012 at 13:16 Last updated: 24th Oct 2013 at 16:17
Authors: Lars Ole Schwen, Tobias Preusser
DOI: 10.1155/2012/357687
Date Published: 2012
Projects: D1: Regulation of Blood Flow and Perfusion in the Liver, E3: Horizontal integration on organ scale, E4: Vertical integration across biological scales
Journal: International Journal of Hepatology
Citation: International Journal of Hepatology 2012(3) : 1
Scales: Liver
Abstract (Expand)
Created: 27th Sep 2012 at 16:42 Last updated: 24th Oct 2013 at 16:17
Authors: C. Mente, I. Prade, L. Brusch, G. Breier, A. Deutsch
DOI: 10.5506/APhysPolBSupp.5.99
Date Published: 20th Dec 2011
Projects: C2: Organization of the sinusoidal system and the liver lobule - referen..., D4: Regeneration and Liver Size
Journal: Acta Phys. Pol. B
Citation: Acta Phys. Pol. B Proc. Suppl. 5(1) : 99
Scales: Not specified
Abstract (Expand)
Created: 23rd Oct 2012 at 15:55 Last updated: 24th Oct 2013 at 16:17
Authors: Josef Wanninger, Sabrina Bauer, Kristina Eisinger, Thomas S Weiss, Roland Walter, Claus Hellerbrand, Andreas Schäffler, Akiko Higuchi, Kenneth Walsh, Christa Buechler
PubMed ID: 22118966
Date Published: 18th Nov 2011
Projects: CTU SOP Human Hepatocytes, Show cases
Journal: Mol. Cell. Endocrinol.
Citation: Mol. Cell. Endocrinol. 349(2): 248-54
A methionine-choline-deficient diet elicits NASH in the immunodeficient mouse featuring a model for hepatic cell transplantation
Authors: Sandra Pelz, Peggy Stock, Sandra Brückner, Bruno Christ
PubMed ID: 22108588
Date Published: 13th Nov 2011
Projects: C6: Organization and function of the sinusoidal system and the liver lob...
Journal: Exp. Cell Res.
Citation: Exp. Cell Res. 318(3): 276-87
Scales: Cell, Liver lobule and Liver
Abstract (Expand)
Created: 16th Aug 2012 at 08:13 Last updated: 24th Oct 2013 at 16:17
Authors: Katrin Hübner, Sven Sahle, Ursula Kummer
PubMed ID: 21707921
Date Published: 26th Jul 2011
Scales: Cell
Abstract (Expand)
Created: 30th Aug 2012 at 13:14 Last updated: 24th Oct 2013 at 16:18
Authors: A. Bischoff, M. Eibisch, B. Fuchs, R. Süss, M. Schürenberg, D. Suckau, J. Schiller
DOI: 10.1556/AChrom.23.2011.2.13
Date Published: 1st Jun 2011
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...
Journal: Acta Chromatographica
Citation: Acta Chromatographica 23(2) : 365
Scales: Not specified
Abstract (Expand)
Created: 23rd Jun 2011 at 17:24 Last updated: 24th Oct 2013 at 16:18
A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes
Authors: Joachim Bucher, Stephan Riedmaier, Anke Schnabel, Katrin Marcus, Gabriele Vacun, Thomas S Weiss, Wolfgang E Thasler, Andreas K Nüssler, Ulrich M Zanger, Matthias Reuss
PubMed ID: 21548957
Date Published: 6th May 2011
Projects: A3.4: Linking signalling to metabolic functions
Journal: BMC Syst Biol
Citation: BMC Syst Biol 5: 66
Scales: Not specified
Abstract (Expand)
Created: 31st Jan 2012 at 11:59 Last updated: 24th Oct 2013 at 16:18
Authors: A Raue, C Kreutz, T Maiwald, U Klingmuller, J Timmer
PubMed ID: 21405200
Date Published: 17th Mar 2011
Projects: A2.1: Multi-level regulation of signalling pathways important for primin..., A2.3: Cross-talk and distinct properties of growth factor signalling reg..., A2.5: Integration of insulin and Wnt signalling in hepatocytes, B2.1: Hepatic stellate cells as source and target for hepatocellular gro...
Journal: IET Syst Biol
Citation: IET Syst Biol 5(2): 120-30
Scales: Cell and Intercellular
Abstract (Expand)
Created: 18th Jul 2012 at 09:24 Last updated: 24th Oct 2013 at 16:18
ABCB1 single-nucleotide polymorphisms determine tacrolimus response in patients with ulcerative colitis
Authors: K R Herrlinger, H Koc, S Winter, A Teml, E F Stange, K Fellermann, P Fritz, M Schwab, E Schaeffeler
PubMed ID: 21289623
Date Published: 2nd Feb 2011
Projects: G2: Clinical Translation to Non-Invasive Volunteer Setting
Journal: Clin. Pharmacol. Ther.
Citation: Clin. Pharmacol. Ther. 89(3): 422-8
Scales: Not specified
Abstract (Expand)
Created: 18th Jul 2012 at 12:30 Last updated: 24th Oct 2013 at 16:19
Authors: André Homeyer, Uta Dahmen, Hai Huang, Andrea Schenk, Olaf Dirsch, HorstK Hahn
Date Published: 2011
Projects: D4: Regeneration and Liver Size
Journal: J Pathol Inform
Citation: J Pathol Inform 2(2) : 11
Scales: Liver
Abstract (Expand)
Created: 9th Mar 2012 at 15:42 Last updated: 24th Oct 2013 at 16:19
Automated extraction of DNA and RNA from a single formalin-fixed paraffin-embedded tissue section for analysis of both single-nucleotide polymorphisms and mRNA expression
Authors: Guido Hennig, Mathias Gehrmann, Udo Stropp, Hiltrud Brauch, Peter Fritz, Michel Eichelbaum, Matthias Schwab, Werner Schroth
PubMed ID: 20947696
Date Published: 14th Oct 2010
Projects: No Projects
Journal: Clin. Chem.
Citation: Clin. Chem. 56(12): 1845-53
Scales: Not specified
Abstract (Expand)
Created: 18th Jul 2012 at 12:20 Last updated: 24th Oct 2013 at 16:19
Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis
Authors: Carola Huthmacher, Andreas Hoppe, Sascha Bulik, Hermann-Georg Holzhütter
PubMed ID: 20807400
Date Published: 31st Aug 2010
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...
Journal: BMC Syst Biol
Citation: BMC Syst Biol 4: 120
Scales: Cell
Abstract (Expand)
Created: 4th Jan 2013 at 10:50 Last updated: 24th Oct 2013 at 16:19
Authors: Stefan Hoehme, Dirk Drasdo
PubMed ID: 20709692
Date Published: 13th Aug 2010
Projects: No Projects
Journal: Bioinformatics
Citation: Bioinformatics 26(20): 2641-2
Scales: Not specified
Abstract (Expand)
Created: 10th Sep 2012 at 17:45 Last updated: 24th Oct 2013 at 16:19
Authors: Irina Nazarenko, Marcel Jenny, Jana Keil, Cornelia Gieseler, Karen Weisshaupt, Jalid Sehouli, Stefan Legewie, Lena Herbst, Wilko Weichert, Silvia Darb-Esfahani, Manfred Dietel, Reinhold Schäfer, Florian Ueberall, Christine Sers
PubMed ID: 20501645
Date Published: 25th May 2010
Projects: A2.3: Cross-talk and distinct properties of growth factor signalling reg..., B2.1: Hepatic stellate cells as source and target for hepatocellular gro...
Journal: Mol. Cancer Res.
Citation: Mol. Cancer Res. 8(6): 919-34
Scales: Cell
Abstract (Expand)
Created: 11th Sep 2012 at 11:39 Last updated: 24th Oct 2013 at 16:20
Authors: Beate Fuchs, Rosmarie Süss, Jürgen Schiller
PubMed ID: 20643161
Date Published: 25th Apr 2010
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...
Journal: Prog. Lipid Res.
Citation: Prog. Lipid Res. 49(4): 450-75
Scales: Not specified
Abstract (Expand)
Created: 23rd Jun 2011 at 17:13 Last updated: 24th Oct 2013 at 16:20
Authors: Andreas Dräger, Adrian Schröder, Andreas Zell
DOI: 10.1007/978-1-4419-5797-9_7
Date Published: 2010
Projects: A3.4: Linking signalling to metabolic functions
Book: Systems Biology for Signaling Networks
Citation: Systems Biology for Signaling Networks : 159
Scales: Not specified
Abstract (Expand)
Created: 11th Jul 2011 at 09:40 Last updated: 24th Oct 2013 at 16:20
Authors: R Schlatter, H Conzelmann, E D Gilles, O Sawodny, T Sauter
PubMed ID: 19640164
Date Published: 31st Jul 2009
Projects: No Projects
Journal: IET Syst Biol
Citation: IET Syst Biol 3(4): 255-65
Scales: Not specified
Abstract (Expand)
Created: 3rd Dec 2010 at 10:00 Last updated: 24th Oct 2013 at 16:21
Authors: Irina Surovtsova, Natalia Simus, Thomas Lorenz, Artjom König, Sven Sahle, Ursula Kummer
PubMed ID: 19633098
Date Published: 24th Jul 2009
Scales: Not specified
Abstract (Expand)
Created: 30th Aug 2012 at 13:24 Last updated: 24th Oct 2013 at 16:21
Authors: Bernd Binder, Andrean Goede, Nikolaus Berndt, Hermann-Georg Holzhütter
PubMed ID: 20041124
Date Published: 21st Jul 2009
Scales: Not specified
Abstract (Expand)
Created: 4th Feb 2011 at 12:47 Last updated: 24th Oct 2013 at 16:21
A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts
Authors: Nils Blüthgen, Stefan Legewie, Szymon M Kielbasa, Anja Schramme, Oleg Tchernitsa, Jana Keil, Andrea Solf, Martin Vingron, Reinhold Schäfer, Hanspeter Herzel, Christine Sers
PubMed ID: 19154344
Date Published: 12th Jan 2009
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 11:44 Last updated: 24th Oct 2013 at 16:22
Authors: Ilka M Axmann, Stefan Legewie, Hanspeter Herzel
PubMed ID: 18546474
Date Published: 12th Jun 2008
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 13:01 Last updated: 24th Oct 2013 at 16:22
Authors: Anuradha Chauhan, Stefan Legewie, Pål O Westermark, Stephan Lorenzen, Hanspeter Herzel
PubMed ID: 18339403
Date Published: 1st Feb 2008
Scales: Not specified
Abstract (Expand)
Created: 11th Sep 2012 at 13:05 Last updated: 24th Oct 2013 at 16:22
A computational analysis of protein interactions in metabolic networks reveals novel enzyme pairs potentially involved in metabolic channeling
Authors: Carola Huthmacher, Christoph Gille, Hermann-Georg Holzhütter
PubMed ID: 17988690
Date Published: 5th Oct 2007
Projects: No Projects
Journal: J. Theor. Biol.
Citation: J. Theor. Biol. 252(3): 456-64
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 13:00 Last updated: 24th Oct 2013 at 16:23
Authors: C Kreutz, M M Bartolome Rodriguez, T Maiwald, M Seidl, H E Blum, L Mohr, J Timmer
PubMed ID: 17768165
Date Published: 3rd Sep 2007
Projects: A2.5: Integration of insulin and Wnt signalling in hepatocytes
Journal: Bioinformatics
Citation: Bioinformatics 23(20): 2747-53
Scales: Not specified
Abstract (Expand)
Created: 10th Dec 2010 at 12:12 Last updated: 24th Oct 2013 at 16:23
Activation of NF-kappaB by IL-1beta blocks IL-6-induced sustained STAT3 activation and STAT3-dependent gene expression of the human gamma-fibrinogen gene
Authors: Ute Albrecht, Xiangping Yang, Rosanna Asselta, Verena Keitel, Maria Luisa Tenchini, Stephan Ludwig, Peter C Heinrich, Dieter Häussinger, Fred Schaper, Johannes G Bode
PubMed ID: 17543500
Date Published: 1st May 2007
Projects: A1.3: Identification of crucial metabolic processes during hepatocyte pr..., A2.2: Regulation of pro-apoptotic and anti-apoptotic responses in hepato..., A2.4: Linking signalling pathways regulating liver regeneration and orga..., A3.2: Cross-talk of signaling pathways and endocytic machinery in hepato...
Journal: Cell. Signal.
Citation: Cell. Signal. 19(9): 1866-78
Scales: Not specified
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Created: 31st Aug 2012 at 11:47 Last updated: 24th Oct 2013 at 16:23