Publications
Advanced filteringAuthors: M. G. Mooij, A. T. Nies, C. A. Knibbe, E. Schaeffeler, D. Tibboel, M. Schwab, S. N. de Wildt
PubMed ID: 26410689
Date Published: 28th Sep 2015
Projects: G2: Clinical Translation to Non-Invasive Volunteer Setting, G3: Clinical Translation to Pharmaceutical Drug Development
Journal: Clin Pharmacokinet
Citation: Clin Pharmacokinet. 2015 Sep 26.
Scales: Not specified
Abstract (Expand)
Created: 17th Dec 2015 at 11:53
Authors: Minjun Chen, Ayako Suzuki, Jürgen Borlak, Raúl J Andrade, M Isabel Lucena
PubMed ID: 25912521
Date Published: 29th Apr 2015
Projects: A1.2: Detoxification in hepatocytes challenged by steatotic conditions, A3.6: Transcription factor network and links to metabolism in NAFLD
Journal: J. Hepatol.
Citation: J. Hepatol. :
Scales: Not specified
Abstract (Expand)
Created: 5th May 2015 at 09:06
Authors: Lorenza A. D’Alessandro, Regina Samaga, Tim Maiwald, Seong-Hwan Rho, Sandra Bonefas, Andreas Raue, Nao Iwamoto, Alexandra Kienast, Katharina Waldow, Rene Meyer, Marcel Schilling, Jens Timmer, Steffen Klamt, Ursula Klingmüller
DOI: 10.1371/journal.pcbi.1004192
Date Published: 23rd Apr 2015
Projects: A2.1: Multi-level regulation of signalling pathways important for primin..., A2.3: Cross-talk and distinct properties of growth factor signalling reg..., A2.4: Linking signalling pathways regulating liver regeneration and orga..., A2: Integration of Signalling Pathways in Hepatocellular Response, A3.2: Cross-talk of signaling pathways and endocytic machinery in hepato..., A3.4: Linking signalling to metabolic functions, E1: Integration on the cellular level, Showcase HGF and Regeneration
Journal: PLoS Comput Biol
Citation: PLoS Comput Biol 11(4) : e1004192
Scales: Cell
Abstract (Expand)
Created: 5th May 2015 at 13:29 Last updated: 22nd May 2015 at 08:57
Authors: Stefan Ohrnberger, Abhishek Thavamani, Albert Braeuning, Daniel B. Lipka, Milen Kirilov, Robert Geffers, Stella E. Authenrieth, Michael Römer, Andreas Zell, Michael Bonin, Michael Schwarz, Günther Schütz, Peter Schirmacher, Christoph Plass, Thomas Longerich, Alfred Nordheim
DOI: 10.1002/hep.27539
Date Published: 1st Mar 2015
Projects: C6: Organization and function of the sinusoidal system and the liver lob...
Journal: Hepatology
Citation: Hepatology 61(3) : 979
Scales: Cell, Intercellular and Liver lobule
Abstract (Expand)
Created: 14th Dec 2015 at 15:12 Last updated: 14th Dec 2015 at 15:15
Authors: David Zakim, Matthias Schwab
PubMed ID: 25479798
Date Published: 2nd Dec 2014
Projects: G3: Clinical Translation to Pharmaceutical Drug Development
Journal: Trends Pharmacol. Sci.
Citation: Trends Pharmacol. Sci. 36(2): 68-71
Scales: Not specified
Abstract (Expand)
Created: 7th Apr 2015 at 14:54
Authors: Ulrike Wittig, Renate Kania, Meik Bittkowski, Elina Wetsch, Lei Shi, Lenneke Jong, Martin Golebiewski, Maja Rey, Andreas Weidemann, Isabel Rojas, Wolfgang Müller
DOI: 10.1016/j.pisc.2014.02.004
Date Published: 1st May 2014
Projects: F3: Kinetic data handling
Journal: Perspectives in Science
Citation: Perspectives in Science 1(1-6) : 33
Scales: Not specified
Abstract (Expand)
Created: 3rd Feb 2015 at 10:55 Last updated: 3rd Feb 2015 at 11:03
Authors: Matthias Jeschke, Stephan Baumgärtner, Stefan Legewie
PubMed ID: 24339758
Date Published: 5th Dec 2013
Projects: A2.4: Linking signalling pathways regulating liver regeneration and orga..., B1.2: Reciprocal effect of cell-cell communication on information proces..., B1.3: Linking modulation of iron metabolism with the impact of macrophag...
Journal: PLoS Comput. Biol.
Citation: PLoS Comput. Biol. 9(12): e1003357
Scales: Not specified
Abstract (Expand)
Created: 20th Jan 2014 at 16:29
Authors: A Köhn-Luque, W de Back, Y Yamaguchi, K Yoshimura, M A Herrero, T Miura
DOI: 10.1088/1478-3975/10/6/066007
Date Published: 1st Dec 2013
Projects: B2.3: Effect of hepatic stellate cells on hepatocyte polarity and transd..., B3: Intercellular communication through cell adhesion, C2: Organization of the sinusoidal system and the liver lobule - referen..., C5: Structural changes and functional consequences of the liver lobular/...
Journal: Phys. Biol.
Citation: Phys. Biol. 10(6) : 066007
Scales: Intercellular
Abstract (Expand)
Created: 24th Jan 2014 at 13:54 Last updated: 24th Jan 2014 at 13:57
Detecting and removing inconsistencies between experimental data and signaling network topologies using integer linear programming on interaction graphs
Authors: Ioannis N Melas, Regina Samaga, Leonidas G Alexopoulos, Steffen Klamt
PubMed ID: 24039561
Date Published: 5th Sep 2013
Projects: A2.3: Cross-talk and distinct properties of growth factor signalling reg...
Journal: PLoS Comput. Biol.
Citation: PLoS Comput. Biol. 9(9): e1003204
DNA methylation of the SLC16A3 promoter regulates expression of the human lactate transporter MCT4 in renal cancer with consequences for clinical outcome
Authors: Pascale Fisel, Stephan Kruck, Stefan Winter, Jens Bedke, Jörg Hennenlotter, Anne T Nies, Marcus Scharpf, Falko Fend, Arnulf Stenzl, Matthias Schwab, Elke Schaeffeler
PubMed ID: 23881922
Date Published: 23rd Jul 2013
Projects: B5: Cell-cell communication influences detoxifying functions in hepatocytes, G3: Clinical Translation to Pharmaceutical Drug Development
Journal: Clin. Cancer Res.
Citation: Clin. Cancer Res. 19(18): 5170-81
Scales: Not specified
Abstract (Expand)
Created: 20th Jan 2014 at 14:16
Differently Saturated Fatty Acids Can Be Differentiated by (31)P NMR Subsequent to Derivatization with 2-Chloro-4,4,5,5-tetramethyldioxaphospholane: A Cautionary Note
Authors: Mandy Eibisch, Thomas Riemer, Beate Fuchs, Jürgen Schiller
PubMed ID: 23414224
Date Published: 26th Feb 2013
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...
Journal: J. Agric. Food Chem.
Citation: J. Agric. Food Chem. 61(11): 2696-700
Scales: Not specified
Abstract (Expand)
Created: 6th Jan 2014 at 13:54
Direct Transcriptional Regulation of Human Hepatic Cytochrome P450 3A4 (CYP3A4) by Peroxisome Proliferator-Activated Receptor Alpha (PPARα)
Authors: Maria Thomas, Oliver Burk, Britta Klumpp, Benjamin A Kandel, Georg Damm, Thomas S Weiss, Kathrin Klein, Matthias Schwab, Ulrich M Zanger
PubMed ID: 23295386
Date Published: 9th Jan 2013
Projects: A1.2: Detoxification in hepatocytes challenged by steatotic conditions, A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes, G1: Clinical Translation to Invasively Characterized Patients, G2: Clinical Translation to Non-Invasive Volunteer Setting, Showcase Steatosis
Journal: Mol. Pharmacol.
Citation: Mol. Pharmacol. 83(3): 709-18
Scales: Cell
Abstract (Expand)
Created: 9th Jan 2013 at 15:04 Last updated: 24th Oct 2013 at 16:15
Authors: Christoph Meyer, Johanna Dzieran, Yan Liu, Felizitas Schindler, Stefan Munker, Alexandra Müller, Cédric Coulouarn, Steven Dooley
Date Published: 2013
Projects: A3.3: Hepatocyte polarity
Journal: Cell Commun Signal
Citation: Cell Commun Signal 11(1) : 6
Scales: Cell
Abstract:
Created: 23rd Jan 2013 at 17:57 Last updated: 24th Oct 2013 at 16:15
Authors: Juliane Gebauer, Stefan Schuster, Luís F de Figueiredo, Christoph Kaleta
PubMed ID: 22776428
Date Published: 11th Jul 2012
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...
Journal: The FEBS journal
Citation: FEBS J. 279(17): 3192-202
Authors: Yijun Wu, Qi Li, Xinhui Zhou, Jiren Yu, Yunchuan Mu, Stefan Munker, Chengfu Xu, Zhe Shen, Roman Müllenbach, Yan Liu, Li Li, Norbert Gretz, Derek Zieker, Jun Li, Kouichi Matsuzaki, Youming Li, Steven Dooley, Honglei Weng
PubMed ID: 22539990
Date Published: 23rd Apr 2012
Projects: A2.3: Cross-talk and distinct properties of growth factor signalling reg..., Show cases
Journal: PLoS ONE
Citation: PLoS ONE 7(4): e35684
Scales: Not specified
Abstract (Expand)
Created: 31st Oct 2012 at 09:13 Last updated: 24th Oct 2013 at 16:16
Authors: Katja Wegner, Anastasia Bachmann, Jan-Ulrich Schad, Philippe Lucarelli, Sven Sahle, Peter Nickel, Christoph Meyer, Ursula Klingmüller, Steven Dooley, Ursula Kummer
PubMed ID: 22284904
Date Published: 5th Jan 2012
DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma
Authors: Elke Schaeffeler, Claus Hellerbrand, Anne T Nies, Stefan Winter, Stephan Kruck, Ute Hofmann, Heiko van der Kuip, Ulrich M Zanger, Hermann Koepsell, Matthias Schwab
PubMed ID: 22196450
Date Published: 23rd Dec 2011
Projects: C3: Zonation of metabolism and its regulation, G1: Clinical Translation to Invasively Characterized Patients, G2: Clinical Translation to Non-Invasive Volunteer Setting, G3: Clinical Translation to Pharmaceutical Drug Development, G4: Whole-Body Detoxification in Mouse Models
Journal: Genome Med
Citation: Genome Med 3(12): 82
Scales: Cell
Abstract (Expand)
Created: 27th Jun 2012 at 15:59 Last updated: 24th Oct 2013 at 16:17
Distinct functions of the mitogen-activated protein kinase-activated protein (MAPKAP) kinases MK2 and MK3: MK2 mediates lipopolysaccharide-induced signal transducers and activators of transcription 3 (STAT3) activation by preventing negative regulatory effects of MK3
Authors: Christian Ehlting, Natalia Ronkina, Oliver Böhmer, Ute Albrecht, Konrad A Bode, Karl S Lang, Alexey Kotlyarov, Danuta Radzioch, Matthias Gaestel, Dieter Häussinger, Johannes G Bode
PubMed ID: 21586572
Date Published: 17th May 2011
Projects: B1.1: Differential communication of wound healing and hepatoxic macropha..., B1.2: Reciprocal effect of cell-cell communication on information proces...
Journal: J. Biol. Chem.
Citation: J. Biol. Chem. 286(27): 24113-24
Scales: Cell
Abstract (Expand)
Created: 31st Aug 2012 at 11:46 Last updated: 24th Oct 2013 at 16:18
Authors: Christa Buechler, Thomas S Weiss
PubMed ID: 21222589
Date Published: 13th Jan 2011
Projects: A1.2: Detoxification in hepatocytes challenged by steatotic conditions, A2: Integration of Signalling Pathways in Hepatocellular Response
Journal: Curr. Drug Metab.
Citation: Curr. Drug Metab. 12(1): 24-34
Dynamic mathematical modeling of IL13-induced signaling in Hodgkin and primary mediastinal B-cell lymphoma allows prediction of therapeutic targets
Authors: Valentina Raia, Marcel Schilling, Martin Böhm, Bettina Hahn, Andreas Kowarsch, Andreas Raue, Carsten Sticht, Sebastian Bohl, Maria Saile, Peter Möller, Norbert Gretz, Jens Timmer, Fabian Theis, Wolf-Dieter Lehmann, Peter Lichter, Ursula Klingmüller
PubMed ID: 21127196
Date Published: 2nd Dec 2010
Scales: Not specified
Abstract (Expand)
Created: 10th Aug 2012 at 09:41 Last updated: 24th Oct 2013 at 16:19
Authors: Thomas Maiwald, Jens Timmer
PubMed ID: 18614583
Date Published: 9th Jul 2008
Scales: Not specified
Abstract (Expand)
Created: 17th Aug 2012 at 10:13 Last updated: 24th Oct 2013 at 16:22
Authors: Thomas Maiwald, Clemens Kreutz, Andrea C Pfeifer, Sebastian Bohl, Ursula Klingmüller, Jens Timmer
PubMed ID: 18033750
Date Published: 24th Nov 2007
Scales: Not specified
Abstract (Expand)
Created: 17th Aug 2012 at 10:21 Last updated: 24th Oct 2013 at 16:23
Authors: S Hengl, C Kreutz, J Timmer, T Maiwald
PubMed ID: 17660526
Date Published: 28th Jul 2007
Scales: Not specified
Abstract (Expand)
Created: 17th Aug 2012 at 10:25 Last updated: 24th Oct 2013 at 16:23
Authors: Kilian Bartholomé, Maria Rius, Katrin Letschert, Daniela Keller, Jens Timmer, Dietrich Keppler
PubMed ID: 17548463
Date Published: 4th Jun 2007
Scales: Not specified
Abstract (Expand)
Created: 25th Jul 2011 at 16:51 Last updated: 24th Oct 2013 at 16:23
Authors: A. Schmoldt, H. F. Benthe, G. Haberland
PubMed ID: 10
Date Published: 1st Sep 1975
Projects: A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes
Journal: Biochem Pharmacol
Citation: Biochem Pharmacol. 1975 Sep 1;24(17):1639-41.
Scales: Not specified
Abstract:
Created: 17th Nov 2015 at 12:27
