Publications
Advanced filteringAuthors: J. Matthaei, J. Brockmoller, M. V. Tzvetkov, D. Sehrt, C. Sachse-Seeboth, J. B. Hjelmborg, S. Moller, U. Halekoh, U. Hofmann, M. Schwab, R. Kerb
PubMed ID: 26344676
Date Published: 8th Sep 2015
Projects: G2: Clinical Translation to Non-Invasive Volunteer Setting, G3: Clinical Translation to Pharmaceutical Drug Development
Journal: Clin Pharmacol Ther
Citation: Clin Pharmacol Ther. 2015 Sep 7. doi: 10.1002/cpt.258.
Scales: Not specified
Abstract (Expand)
Created: 17th Dec 2015 at 11:46
Authors: Christoph Meyer, Roman Liebe, Katja Breitkopf-Heinlein, Yan Liu, Alexandra Müller, Pia Rakoczy, Maria Thomas, Honglei Weng, Anastasia Bachmann, Matthias Ebert, Steven Dooley
PubMed ID: 25982745
Date Published: 20th May 2015
Projects: A2.2: Regulation of pro-apoptotic and anti-apoptotic responses in hepato..., A3.3: Hepatocyte polarity
Journal: Differentiation
Citation: Differentiation :
Human sterol regulatory element-binding protein 1a contributes significantly to hepatic lipogenic gene expression
Authors: Andreas Bitter, Andreas K Nüssler, Wolfgang E Thasler, Kathrin Klein, Ulrich M Zanger, Matthias Schwab, Oliver Burk
PubMed ID: 25634759
Date Published: 30th Jan 2015
Projects: A1.2: Detoxification in hepatocytes challenged by steatotic conditions, A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes, G2: Clinical Translation to Non-Invasive Volunteer Setting, G3: Clinical Translation to Pharmaceutical Drug Development, Showcase Steatosis
Journal: Cell. Physiol. Biochem.
Citation: Cell. Physiol. Biochem. 35(2): 803-15
Scales: Not specified
Abstract (Expand)
Created: 7th Apr 2015 at 14:59
Authors: Dirk Drasdo, Stefan Hoehme, Jan G. Hengstler
DOI: 10.1016/j.jhep.2014.06.013
Date Published: 1st Oct 2014
Projects: C: Liver lobule level
Journal: Journal of Hepatology
Citation: Journal of Hepatology 61(4) : 951
Scales: Not specified
Abstract:
Created: 7th Nov 2014 at 15:09 Last updated: 7th Nov 2014 at 15:09
Human mesenchymal stem cells towards non-alcoholic steatohepatitis in an immunodeficient mouse model
Authors: Sandra Winkler, Erawan Borkham-Kamphorst, Peggy Stock, Sandra Brückner, Matthias Dollinger, Ralf Weiskirchen, Bruno Christ
PubMed ID: 24786317
Date Published: 3rd May 2014
Projects: C4: Disturbance of liver lobule organization in NAFLD, C6: Organization and function of the sinusoidal system and the liver lob..., G: Clinical translation, Showcase Steatosis
Journal: Exp. Cell Res.
Citation: Exp. Cell Res. :
Human bone marrow mesenchymal stem cell-derived hepatocytes improve the mouse liver after acute acetaminophen intoxication by preventing progress of injury
Authors: Peggy Stock, Sandra Brückner, Sandra Winkler, Matthias M Dollinger, Bruno Christ
PubMed ID: 24758938
Date Published: 25th Apr 2014
Projects: A1: Cellular metabolism, C6: Organization and function of the sinusoidal system and the liver lob..., G: Clinical translation, Showcase HGF and Regeneration
Journal: Int J Mol Sci
Citation: Int J Mol Sci 15(4): 7004-28
Scales: Liver lobule and Liver
Abstract (Expand)
Created: 19th May 2014 at 20:04
Authors: Jürgen Borlak, Anil Chougule, Prafull Kumar Singh
PubMed ID: 24685772
Date Published: 2nd Apr 2014
Projects: A1.2: Detoxification in hepatocytes challenged by steatotic conditions
Journal: Toxicol In Vitro
Citation: Toxicol In Vitro :
Authors: Nadine Hohmann, Wei Weiwei, Uta Dahmen, Olaf Dirsch, Andreas Deutsch, Anja Voss-Böhme
DOI: 10.1371/journal.pone.0093207
Date Published: 1st Apr 2014
Scales: Intercellular, Liver lobule and Liver
Abstract (Expand)
Created: 24th Apr 2014 at 14:21 Last updated: 24th Apr 2014 at 14:26
Authors: Madlen Matz-Soja, Susanne Aleithe, Eugenia Marbach, Jan Böttger, Katrin Arnold, Wolfgang Schmidt-Heck, Jürgen Kratzsch, Rolf Gebhardt
PubMed ID: 24548465
Date Published: 18th Feb 2014
Authors: Georg Damm, Elisa Pfeiffer, Britta Burkhardt, Jan Vermehren, Andreas K. Nüssler, Thomas S. Weiss
DOI: 10.1007/s12072-013-9475-7
Date Published: 1st Oct 2013
Projects: CTU SOP Hepatic stellate cells, human, CTU SOP Human Hepatocytes, CTU SOP Kupffer cells/macrophages, human, CTU SOP Liver sinusoidal endothelial cells, human
Journal: Hepatol Int
Citation: Hepatol Int 7(4) : 951
Scales: Cell
Abstract:
Created: 30th Jan 2014 at 16:52 Last updated: 30th Jan 2014 at 16:54
Hedgehog signalling pathway in adult liver: a major new player in hepatocyte metabolism and zonation
Authors: Madlen Matz-Soja, Amalya Hovhannisyan, Rolf Gebhardt
PubMed ID: 23433827
Date Published: 21st Feb 2013
High lipophilicity and high daily dose of oral medications are associated with significant risk for drug-induced liver injury
Authors: Minjun Chen, Jürgen Borlak, Weida Tong
PubMed ID: 23258593
Date Published: 22nd Dec 2012
Projects: A1.2: Detoxification in hepatocytes challenged by steatotic conditions
Journal: Hepatology
Citation: Hepatology 58(1): 388-96
Scales: Liver
Abstract (Expand)
Created: 28th Jan 2013 at 13:20 Last updated: 24th Oct 2013 at 16:15
Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment
Authors: Lars Wiechert, Julia Németh, Tobias Pusterla, Christine Bauer, Aurora De Ponti, Sandra Manthey, Silke Marhenke, Arndt Vogel, Ursula Klingmüller, Jochen Hess, Peter Angel
PubMed ID: 23241281
Date Published: 15th Dec 2012
Projects: No Projects
Journal: Cell Commun. Signal
Citation: Cell Commun. Signal 10(1): 40
Scales: Not specified
Abstract:
Created: 10th Jan 2013 at 14:31 Last updated: 24th Oct 2013 at 16:15
Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration
Authors: René Meyer, Lorenza A D'Alessandro, Sandip Kar, Bernhard Kramer, Bin She, Daniel Kaschek, Bettina Hahn, David Wrangborg, Johan Karlsson, Mats Kvarnström, Mats Jirstrand, Wolf-Dieter Lehmann, Jens Timmer, Thomas Höfer, Ursula Klingmüller
PubMed ID: 23226133
Date Published: 28th Nov 2012
Projects: No Projects
Journal: Front Physiol
Citation: Front Physiol 3: 451
Scales: Not specified
Abstract (Expand)
Created: 10th Jan 2013 at 14:27 Last updated: 24th Oct 2013 at 16:15
Human pregnane X receptor genotype of the donor but not of the recipient is a risk factor for delayed graft function after renal transplantation
Authors: I A Hauser, S Kruck, S Gauer, A T Nies, S Winter, J Bedke, H Geiger, H Hoefeld, J Kleemann, A Asbe-Vollkopf, J Engel, O Burk, M Schwab, E Schaeffeler
PubMed ID: 22453193
Date Published: 28th Mar 2012
Projects: G2: Clinical Translation to Non-Invasive Volunteer Setting
Journal: Clin. Pharmacol. Ther.
Citation: Clin. Pharmacol. Ther. 91(5): 905-16
Scales: Not specified
Abstract (Expand)
Created: 18th Jul 2012 at 13:01 Last updated: 24th Oct 2013 at 16:16
Hepatic acute phase proteins--regulation by IL-6- and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling
Authors: Johannes G Bode, Ute Albrecht, Dieter Häussinger, Peter C Heinrich, Fred Schaper
PubMed ID: 22093287
Date Published: 16th Nov 2011
Projects: B1.1: Differential communication of wound healing and hepatoxic macropha..., B1.2: Reciprocal effect of cell-cell communication on information proces..., D2: Dynamics of metabolism, inflammation and ammonia detoxication during..., D3: Inflammation and Regeneration: the whole organ
Journal: Eur. J. Cell Biol.
Citation: Eur. J. Cell Biol. 91(6-7): 496-505
Abstract (Expand)
Created: 31st Aug 2012 at 11:44 Last updated: 24th Oct 2013 at 16:17
HMMerThread: detecting remote, functional conserved domains in entire genomes by combining relaxed sequence-database searches with fold recognition
Authors: Charles Richard Bradshaw, Vineeth Surendranath, Robert Henschel, Matthias Stefan Mueller, Bianca Hermine Habermann
PubMed ID: 21423752
Date Published: 16th Nov 2010
Projects: A1.3: Identification of crucial metabolic processes during hepatocyte pr..., A3.2: Cross-talk of signaling pathways and endocytic machinery in hepato..., A3.5: The impact of cell polarity on metabolism detoxification and endoc..., C2: Organization of the sinusoidal system and the liver lobule - referen..., C5: Structural changes and functional consequences of the liver lobular/..., C6: Organization and function of the sinusoidal system and the liver lob...
Journal: PLoS ONE
Citation: PLoS ONE 6(3): e17568
Scales: Not specified
Abstract (Expand)
Created: 24th Jun 2011 at 16:19 Last updated: 24th Oct 2013 at 16:19
HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology
Authors: Christoph Gille, Christian Bölling, Andreas Hoppe, Sascha Bulik, Sabrina Hoffmann, Katrin Hübner, Anja Karlstädt, Ramanan Ganeshan, Matthias König, Kristian Rother, Michael Weidlich, Jörn Behre, Herrmann-Georg Holzhütter
PubMed ID: 20823849
Date Published: 30th Dec 2009
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal..., A1.3: Identification of crucial metabolic processes during hepatocyte pr..., F2: The Liver Knowledge Base (LKB)
Journal: Mol. Syst. Biol.
Citation: Mol. Syst. Biol. 6: 411
Scales: Liver
Abstract (Expand)
Created: 9th Dec 2010 at 13:39 Last updated: 24th Oct 2013 at 16:20
Authors: Sebastian Zellmer, Stephan Sickinger, Wolfgang Schmidt-Heck, Reinhard Guthke, Rolf Gebhardt
PubMed ID: 19470084
Date Published: 14th May 2009
Projects: No Projects
Journal: J. Anat.
Citation: J. Anat. 215(2): 176-83
Scales: Not specified
Abstract (Expand)
Created: 28th Sep 2010 at 09:25 Last updated: 24th Oct 2013 at 16:21
Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage
Authors: Steven Dooley, Jafar Hamzavi, Loredana Ciuclan, Patricio Godoy, Iryna Ilkavets, Sabrina Ehnert, Elke Ueberham, Rolf Gebhardt, Stephan Kanzler, Andreas Geier, Katja Breitkopf, Honglei Weng, Peter R Mertens
PubMed ID: 18602923
Date Published: 15th May 2008
Projects: A3.3: Hepatocyte polarity, HepatoSys
Journal: Gastroenterology
Citation: Gastroenterology 135(2): 642-59
Scales: Not specified
Abstract (Expand)
Created: 24th Feb 2012 at 17:08 Last updated: 24th Oct 2013 at 16:22
