Publications
Advanced filteringAuthors: N. J. Stanford, K. Wolstencroft, M. Golebiewski, R. Kania, N. Juty, C. Tomlinson, S. Owen, S. Butcher, H. Hermjakob, N. Le Novere, W. Mueller, J. Snoep, C. Goble
PubMed ID: 26700851
Date Published: 25th Dec 2015
Projects: F1: The data management system, Virtual Liver
Journal: Mol Syst Biol
Citation: Mol Syst Biol. 2015 Dec 23;11(12):851. doi: 10.15252/msb.20156053.
Scales: Not specified
Abstract:
Created: 8th Jan 2016 at 09:38
Authors: B. Christ, S. Bruckner, S. Winkler
PubMed ID: 26476857
Date Published: 22nd Oct 2015
Projects: C6: Organization and function of the sinusoidal system and the liver lob...
Journal: Trends Mol Med
Citation: Trends Mol Med. 2015 Nov;21(11):673-86. doi: 10.1016/j.molmed.2015.09.004. Epub 2015 Oct 22.
The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPARalpha-tr, autonomously regulates proliferative and pro-inflammatory genes
Authors: M. Thomas, C. Bayha, K. Klein, S. Muller, T. S. Weiss, M. Schwab, U. M. Zanger
PubMed ID: 26122096
Date Published: 30th Jun 2015
Projects: A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes
Journal: BMC Cancer
Citation: BMC Cancer. 2015 Jun 30;15:488. doi: 10.1186/s12885-015-1500-x.
Scales: Not specified
Abstract (Expand)
Created: 17th Sep 2015 at 10:19
Authors: J. M. Villaveces, P. Koti, B. H. Habermann
PubMed ID: 26082651
Date Published: 4th Jun 2015
Projects: A1.3: Identification of crucial metabolic processes during hepatocyte pr..., A3.2: Cross-talk of signaling pathways and endocytic machinery in hepato..., A3.5: The impact of cell polarity on metabolism detoxification and endoc..., C2: Organization of the sinusoidal system and the liver lobule - referen..., C5: Structural changes and functional consequences of the liver lobular/..., C6: Organization and function of the sinusoidal system and the liver lob...
Journal: Adv Appl Bioinform Chem
Citation: Adv Appl Bioinform Chem. 2015 Jun 4;8:11-22. doi: 10.2147/AABC.S63534. eCollection 2015.
Scales: Not specified
Abstract (Expand)
Created: 18th Dec 2015 at 12:57
Authors: Aidan Budd, Holger Dinkel, Manuel Corpas, Jonathan C. Fuller, Laura Rubinat, Damien P. Devos, Pierre H. Khoueiry, Konrad U. Förstner, Fotis Georgatos, Francis Rowland, Malvika Sharan, Janos X. Binder, Tom Grace, Karyn Traphagen, Adam Gristwood, Natasha T. Wood
DOI: 10.1371/journal.pcbi.1003905
Date Published: 29th Jan 2015
Projects: No Projects
Journal: PLoS Comput Biol
Citation: PLoS Comput Biol 11(1) : e1003905
Scales: Not specified
Abstract:
Created: 2nd Feb 2015 at 14:43 Last updated: 2nd Feb 2015 at 14:47
Authors: Dirk Drasdo, Johannes Bode, Uta Dahmen, Olaf Dirsch, Steven Dooley, Rolf Gebhardt, Ahmed Ghallab, Patricio Godoy, Dieter Häussinger, Seddik Hammad, Stefan Hoehme, Hermann-Georg Holzhütter, Ursula Klingmüller, Lars Kuepfer, Jens Timmer, Marino Zerial, Jan G. Hengstler
DOI: 10.1007/s00204-014-1384-6
Date Published: 21st Oct 2014
Projects: No Projects
Journal: Arch Toxicol
Citation: Arch Toxicol
Scales: Not specified
Abstract:
Created: 7th Nov 2014 at 15:06 Last updated: 7th Nov 2014 at 15:06
Author: Adriano Henney
DOI: 10.4155/FMC.14.127
Date Published: 1st Oct 2014
Projects: No Projects
Journal: Future Medicinal Chemistry
Citation: Future Medicinal Chemistry 6(16) : 1735
Scales: Not specified
Abstract:
Created: 28th Nov 2014 at 17:48
Authors: Sandra Winkler, Bruno Christ
PubMed ID: 25173373
Date Published: 1st Sep 2014
Projects: C6: Organization and function of the sinusoidal system and the liver lob..., Showcase Steatosis
Journal: Methods Mol. Biol.
Citation: Methods Mol. Biol. 1213: 51-6
The many faces of Hedgehog signalling in the liver: Recent progress reveals striking cellular diversity and the importance of microenvironments
Authors: Madlen Matz-Soja, Rolf Gebhardt
PubMed ID: 25152210
Date Published: 26th Aug 2014
Scales: Not specified
Abstract:
Created: 1st Dec 2014 at 15:54
Authors: Maria Thomas, Jessica K Rieger, Benjamin A Kandel, Kathrin Klein, Ulrich M Zanger
PubMed ID: 25012546
Date Published: 1st Jul 2014
Projects: A: Cellular level, B: Communication of Hepatocytes and Non-Parenchymal Liver Cells, C: Liver lobule level
Journal: Cell. Physiol. Biochem.
Citation: Cell. Physiol. Biochem. 33(6): 2003-2013
Scales: Not specified
Abstract (Expand)
Created: 14th Jul 2014 at 13:17
The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity
Authors: Gisela Campos, Wolfgang Schmidt-Heck, Ahmed Ghallab, Katharina Rochlitz, Larissa Pütter, Danilo B Medinas, Claudio Hetz, Agata Widera, Cristina Cadenas, Brigitte Begher-Tibbe, Raymond Reif, Georgia Günther, Agapios Sachinidis, Jan G Hengstler, Patricio Godoy
PubMed ID: 24748426
Date Published: 20th Apr 2014
Projects: C2: Organization of the sinusoidal system and the liver lobule - referen..., C6: Organization and function of the sinusoidal system and the liver lob..., Showcase HGF and Regeneration
Journal: Arch. Toxicol.
Citation: Arch. Toxicol. 88(6): 1267-80
Scales: Not specified
Abstract (Expand)
Created: 20th Jan 2015 at 13:25
Authors: Minjun Chen, Halil Bisgin, Lillian Tong, Huixiao Hong, Hong Fang, Jürgen Borlak, Weida Tong
PubMed ID: 24521015
Date Published: 14th Feb 2014
Projects: A1.2: Detoxification in hepatocytes challenged by steatotic conditions
Journal: Biomark Med
Citation: Biomark Med 8(2): 201-13
Authors: C Borner, D W Andrews
PubMed ID: 24413197
Date Published: 15th Jan 2014
Projects: No Projects
Journal: Cell Death Differ.
Citation: Cell Death Differ. 21(2): 187-91
Scales: Not specified
Abstract:
Created: 22nd Jan 2014 at 15:13
TFpredict and SABINE: Sequence-Based Prediction of Structural and Functional Characteristics of Transcription Factors
Authors: Johannes Eichner, Florian Topf, Andreas Dräger, Clemens Wrzodek, Dierk Wanke, Andreas Zell
DOI: 10.1371/journal.pone.0082238
Date Published: 12th Dec 2013
Projects: A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes
Journal: PLoS ONE
Citation: PLoS ONE 8(12) : e82238
Scales: Cell and Intercellular
Abstract (Expand)
Created: 17th Nov 2015 at 12:27 Last updated: 17th Nov 2015 at 12:28
TNFα-induced lysosomal membrane permeability is downstream of MOMP and triggered by caspase-mediated NDUFS1 cleavage and ROS formation
Authors: Jisen Huai, F-Nora Vögtle, Lars Jöckel, Yunbo Li, Thomas Kiefer, Jean-Ehrland Ricci, Christoph Borner
PubMed ID: 23788428
Date Published: 20th Jun 2013
Projects: No Projects
Journal: J. Cell. Sci.
Citation: J. Cell. Sci. 126(Pt 17): 4015-25
Scales: Not specified
Abstract (Expand)
Created: 22nd Jan 2014 at 15:18
Authors: Nikolaus Berndt, Hermann-Georg Holzhütter
PubMed ID: 23479331
Date Published: 13th Mar 2013
Projects: No Projects
Journal: Cell Biochem. Biophys.
Citation: Cell Biochem Biophys. 67(2):527-35
Scales: Not specified
Abstract (Expand)
Created: 6th May 2013 at 09:24 Last updated: 24th Oct 2013 at 16:14
Authors: M Chen, J Zhang, Y Wang, Z Liu, R Kelly, G Zhou, H Fang, J Borlak, W Tong
PubMed ID: 23486446
Date Published: 25th Jan 2013
Projects: A1.2: Detoxification in hepatocytes challenged by steatotic conditions
Journal: Clin. Pharmacol. Ther.
Citation: Clin. Pharmacol. Ther. 93(5): 409-12
Scales: Cell
Abstract:
Created: 15th Mar 2013 at 14:16 Last updated: 24th Oct 2013 at 16:15
Authors: Roland Keller, Alexander Dörr, Akito Tabira, Akira Funahashi, Michael J Ziller, Richard Adams, Nicolas Rodriguez, Nicolas Le Novère, Noriko Hiroi, Hannes Planatscher, Andreas Zell, Andreas Dräger
Date Published: 2013
Projects: A3.4: Linking signalling to metabolic functions, B5: Cell-cell communication influences detoxifying functions in hepatocytes
Journal: BMC Syst Biol
Citation: BMC Syst Biol 7(1) : 55
Scales: Cell, Intercellular, Liver lobule, Liver and Organism
Abstract (Expand)
Created: 9th Jul 2013 at 04:12 Last updated: 24th Oct 2013 at 16:15
The Extended TILAR Approach: A novel tool for dynamic modeling of the transcription factor network regulating the adaption to in vitro cultivation of murine hepatocytes
Authors: Sebastian Vlaic, Wolfgang Schmidt-Heck, Madlen Matz-Soja, Eugenia Marbach, Jörg Linde, Anke Meyer-Baese, Sebastian Zellmer, Reinhard Guthke, Rolf Gebhardt
PubMed ID: 23190768
Date Published: 29th Nov 2012
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal..., A3.6: Transcription factor network and links to metabolism in NAFLD
Journal: BMC Syst Biol
Citation: BMC Syst Biol 6: 147
Scales: Cell
Abstract (Expand)
Created: 30th Nov 2012 at 14:57 Last updated: 24th Oct 2013 at 16:15
The Process-Interaction-Model: a common representation of rule-based and logical models allows studying signal transduction on different levels of detail
Authors: Katrin Kolczyk, Regina Samaga, Holger Conzelmann, Sebastian Mirschel, Carsten Conradi
PubMed ID: 23020215
Date Published: 28th Sep 2012
Projects: E1: Integration on the cellular level
Journal: BMC Bioinformatics
Citation: BMC Bioinformatics 13: 251
Authors: Christoph Thiele, Cyrus Papan, Dominik Hoelper, Kalina Kusserow, Anne Gaebler, Mario Schoene, Kira Piotrowitz, Daniel Lohmann, Johanna Spandl, Ana Stevanovic, Andrej Shevchenko, Lars Kuerschner
PubMed ID: 22999348
Date Published: 25th Sep 2012
Scales: Cell
Abstract (Expand)
Created: 26th Oct 2012 at 16:36 Last updated: 24th Oct 2013 at 16:15
Tissue proteomics by one-dimensional gel electrophoresis combined with label-free protein quantification
Authors: Andrej Vasilj, Marc Gentzel, Elke Ueberham, Rolf Gebhardt, Andrej Shevchenko
PubMed ID: 22671763
Date Published: 21st Jun 2012
Scales: Cell
Abstract (Expand)
Created: 20th Jul 2012 at 10:20 Last updated: 24th Oct 2013 at 16:16
The promise and challenge of personalized medicine: aging populations, complex diseases, and unmet medical need
Author: Adriano M Henney
PubMed ID: 22661132
Date Published: 5th Jun 2012
Projects: Project Management, Virtual Liver
Journal: Croat. Med. J.
Citation: Croat. Med. J. 53(3): 207-10
Scales: Not specified
Abstract (Expand)
Created: 12th Jun 2012 at 10:11 Last updated: 24th Oct 2013 at 16:16
Time-dependent intensity changes of free fatty acids detected by matrix-assisted laser desorption and ionization time-of-flight mass spectrometry in the presence of 1,8-bis-(dimethylamino)naphthalene--a cautionary note
Authors: Mandy Eibisch, Rosmarie Süss, Jürgen Schiller
PubMed ID: 22638975
Date Published: 29th May 2012
Projects: No Projects
Journal: Rapid Commun. Mass Spectrom.
Citation: Rapid Commun. Mass Spectrom. 26(13): 1573-6
Scales: Not specified
Abstract:
Created: 4th Aug 2012 at 16:26 Last updated: 24th Oct 2013 at 16:16
Authors: C Kreutz, J S Gehring, D Lang, R Reski, J Timmer, S A Rensing
PubMed ID: 22513994
Date Published: 17th Apr 2012
Projects: A2: Integration of Signalling Pathways in Hepatocellular Response
Journal: Bioinformatics
Citation: Bioinformatics 28(12): 1641-2
Scales: Cell
Abstract (Expand)
Created: 8th Aug 2012 at 12:11 Last updated: 24th Oct 2013 at 16:16
The interaction properties of the human Rab GTPase family--comparative analysis reveals determinants of molecular binding selectivity
Authors: Matthias Stein, Manohar Pilli, Sabine Bernauer, Bianca H Habermann, Marino Zerial, Rebecca C Wade
PubMed ID: 22523562
Date Published: 16th Apr 2012
Projects: A3.2: Cross-talk of signaling pathways and endocytic machinery in hepato...
Journal: PLoS ONE
Citation: PLoS ONE 7(4): e34870
Scales: Cell
Abstract (Expand)
Created: 19th Jul 2012 at 09:45 Last updated: 24th Oct 2013 at 16:16
Authors: Mona Malz, Federico Pinna, Peter Schirmacher, Kai Breuhahn
PubMed ID: 22446689
Date Published: 21st Mar 2012
Projects: A2.4: Linking signalling pathways regulating liver regeneration and orga...
Journal: J. Hepatol.
Citation: J. Hepatol. 57(1): 186-95
Scales: Not specified
Abstract (Expand)
Created: 16th Jan 2013 at 09:04 Last updated: 24th Oct 2013 at 16:16
Authors: Johannes G Bode, Christian Ehlting, Dieter Häussinger
PubMed ID: 22330073
Date Published: 4th Feb 2012
Projects: B1.1: Differential communication of wound healing and hepatoxic macropha..., B1.2: Reciprocal effect of cell-cell communication on information proces...
Journal: Cell. Signal.
Citation: Cell. Signal. 24(6): 1185-94
Scales: Cell
Abstract (Expand)
Created: 31st Aug 2012 at 11:41 Last updated: 24th Oct 2013 at 16:17
Authors: Hermann-Georg Holzhütter, Dirk Drasdo, Tobias Preusser, Jörg Lippert, Adriano M Henney
PubMed ID: 22246674
Date Published: 13th Jan 2012
Projects: Virtual Liver
Journal: Wiley Interdiscip Rev Syst Biol Med
Citation: Wiley Interdiscip Rev Syst Biol Med 4(3): 221-35
Scales: Not specified
Abstract (Expand)
Created: 19th Apr 2012 at 16:03 Last updated: 24th Oct 2013 at 16:17
Authors: Steven Dooley, Peter ten Dijke
PubMed ID: 22006249
Date Published: 19th Oct 2011
Projects: B2.3: Effect of hepatic stellate cells on hepatocyte polarity and transd..., Show cases
Journal: Cell Tissue Res.
Citation: Cell Tissue Res. 347(1): 245-56
Scales: Not specified
Abstract (Expand)
Created: 31st Oct 2012 at 08:42 Last updated: 24th Oct 2013 at 16:17
Transcriptional profiling of human liver identifies sex-biased genes associated with polygenic dyslipidemia and coronary artery disease
Authors: Yijing Zhang, Kathrin Klein, Aarathi Sugathan, Najlla Nassery, Alan Dombkowski, Ulrich M Zanger, David J Waxman
PubMed ID: 21858147
Date Published: 12th Aug 2011
Projects: A3.4: Linking signalling to metabolic functions
Journal: PLoS ONE
Citation: PLoS ONE 6(8): e23506
Scales: Not specified
Abstract (Expand)
Created: 14th May 2012 at 09:54 Last updated: 24th Oct 2013 at 16:17
Authors: Mirco Castoldi, Maja Vujic Spasic, Sandro Altamura, Joacim Elmén, Morten Lindow, Judit Kiss, Jens Stolte, Richard Sparla, Lorenza A D'Alessandro, Ursula Klingmüller, Robert E Fleming, Thomas Longerich, Hermann J Gröne, Vladimir Benes, Sakari Kauppinen, Matthias W Hentze, Martina U Muckenthaler
PubMed ID: 21364282
Date Published: 3rd Mar 2011
Projects: B1.3: Linking modulation of iron metabolism with the impact of macrophag...
Journal: J. Clin. Invest.
Citation: J. Clin. Invest. 121(4): 1386-96
Scales: Cell, Liver and Organism
Abstract (Expand)
Created: 11th Jul 2012 at 10:47 Last updated: 24th Oct 2013 at 16:19
The influence of the chloride currents on action potential firing and volume regulation of excitable cells studied by a kinetic model
Authors: Nikolaus Berndt, Sabrina Hoffmann, Jan Benda, Hermann-Georg Holzhütter
PubMed ID: 21295041
Date Published: 2nd Feb 2011
Projects: No Projects
Journal: J. Theor. Biol.
Citation: J. Theor. Biol. 276(1): 42-9
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 11:22 Last updated: 24th Oct 2013 at 16:19
Tumor necrosis factor α sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner
Authors: Kathrin Schmich, Rebekka Schlatter, Nadia Corazza, Karine Sá Ferreira, Michael Ederer, Thomas Brunner, Christoph Borner, Irmgard Merfort
PubMed ID: 20872776
Date Published: 24th Sep 2010
Projects: A2.2: Regulation of pro-apoptotic and anti-apoptotic responses in hepato...
Journal: Hepatology
Citation: Hepatology 53(1): 282-92
Scales: Cell and Intercellular
Abstract (Expand)
Created: 16th Jul 2012 at 16:53 Last updated: 24th Oct 2013 at 16:19
Authors: Matthias W Hentze, Martina U Muckenthaler, Bruno Galy, Clara Camaschella
PubMed ID: 20603012
Date Published: 7th Jul 2010
Projects: B1.3: Linking modulation of iron metabolism with the impact of macrophag..., HepatoSys
Journal: Cell
Citation: Cell 142(1): 24-38
Authors: Peggy Stock, Sandra Brückner, Sabine Ebensing, Madlen Hempel, Matthias M Dollinger, Bruno Christ
PubMed ID: 20224562
Date Published: 11th Mar 2010
Projects: C6: Organization and function of the sinusoidal system and the liver lob...
Journal: Nat Protoc
Citation: Nat Protoc 5(4): 617-27
Transcription factors ETF, E2F, and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes
Authors: Sebastian Zellmer, Wolfgang Schmidt-Heck, Patricio Godoy, Honglei Weng, Christoph Meyer, Thomas Lehmann, Titus Sparna, Wiebke Schormann, Seddik Hammad, Clemens Kreutz, Jens Timmer, Fritz von Weizsäcker, Petra A Thürmann, Irmgard Merfort, Reinhard Guthke, Steven Dooley, Jan G Hengstler, Rolf Gebhardt
PubMed ID: 20979052
Date Published: 5th Mar 2010
Projects: A1.1: Central liver metabolism and its regulation under nutritional chal...
Journal: Hepatology
Citation: Hepatology 52(6): 2127-36
Scales: Not specified
Abstract (Expand)
Created: 13th Dec 2010 at 11:21 Last updated: 24th Oct 2013 at 16:20
The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays
Authors: Yevhen Vainshtein, Mayka Sanchez, Alvis Brazma, Matthias W Hentze, Thomas Dandekar, Martina U Muckenthaler
PubMed ID: 20193060
Date Published: 1st Mar 2010
Scales: Not specified
Abstract (Expand)
Created: 30th Oct 2012 at 08:53 Last updated: 24th Oct 2013 at 16:20
Authors: Peter R Jungblut, Hermann G Holzhütter, Rolf Apweiler, Hartmut Schlüter
PubMed ID: 18638390
Date Published: 18th Jul 2008
Projects: No Projects
Journal: Chem Cent J
Citation: Chem Cent J 2: 16
Scales: Not specified
Abstract (Expand)
Created: 4th Jan 2013 at 13:00 Last updated: 24th Oct 2013 at 16:22
