Publications

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Liu","Y. Wang","J\u00fcrgen Borlak","W. Tong"],"published_year":[2016],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication505","label":"Publication505","display_content":"","type":"Publication","item_id":505,"project":["C1: The role of blood flow in liver lobule function and morphology","D1: Regulation of Blood Flow and Perfusion in the Liver","E3: Horizontal integration on organ scale","E4: Vertical integration across biological scales","Showcase Steatosis"],"author":["Lars Ole Schwen","Andr\u00e9 Homeyer","Michael Schwier","Uta Dahmen","Olaf Dirsch","Arne Schenk","Lars K\u00fcpfer","Tobias Preusser","Andrea Schenk"],"published_year":[2016],"organism":"(Missing value)","tag":"(Missing value)"},{"id":"Publication508","label":"Publication508","display_content":"","type":"Publication","item_id":508,"project":["A1.1: Central liver metabolism and its regulation under nutritional challenges"],"author":["J. Zhang","K. He","L. Cai","Y. C. Chen","Y. Yang","Q. Shi","T. F. Woolf","W. Ge","L. Guo","J\u00fcrgen Borlak","W. Tong"],"published_year":[2016],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication507","label":"Publication507","display_content":"","type":"Publication","item_id":507,"project":["A3.6: Transcription factor network and links to metabolism in NAFLD"],"author":["E. H. Lee","J. H. Oh","Saravanakumar Selvaraj","S. M. Park","M. S. Choi","R. Spanel","S. Yoon","J\u00fcrgen Borlak"],"published_year":[2016],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication502","label":"Publication502","display_content":"","type":"Publication","item_id":502,"project":["A3.4: Linking signalling to metabolic functions","B5: Cell-cell communication influences detoxifying functions in hepatocytes"],"author":["Roland Keller","Marcus Klein","Maria Thomas","Andreas Dr\u00e4ger","Ute Metzger","Markus F. Templin","Thomas Joos","Wolfgang E. Thasler","Andreas Zell","Ulrich Zanger"],"published_year":[2016],"organism":"(Missing value)","tag":["VLN","detoxification","gene-expression","MAPK","signaling","logical modelling","drug metabolism","phosphoproteomics","stat3","primary human hepatocytes","Fuzzy logic","Hepatocytes"]},{"id":"Publication509","label":"Publication509","display_content":"","type":"Publication","item_id":509,"project":["D1: Regulation of Blood Flow and Perfusion in the Liver","D4: Regeneration and Liver Size","E3: Horizontal integration on organ scale","E4: Vertical integration across biological scales"],"author":["Chichi Xie","Weiwei Wei","Andrea Schenk","Lars Ole Schwen","Sara Zafarnia","Michael Schwier","Felix Gremse","Isabel Jank","Olaf Dirsch","Uta Dahmen"],"published_year":[2016],"organism":"(Missing value)","tag":"(Missing value)"},{"id":"Publication503","label":"Publication503","display_content":"","type":"Publication","item_id":503,"project":["F1: The data management system","Virtual Liver"],"author":["N. J. Stanford","K. Wolstencroft","Martin Golebiewski","Renate Kania","N. Juty","C. Tomlinson","S. Owen","S. Butcher","H. Hermjakob","Nicolas Le Nov\u00e8re","Wolfgang M\u00fcller","J. Snoep","C. Goble"],"published_year":[2015],"organism":"(Missing value)","tag":["data management","Virtual Liver SEEK","Standards","VLN"]},{"id":"Publication482","label":"Publication482","display_content":"","type":"Publication","item_id":482,"project":["A3.4: Linking signalling to metabolic functions","B5: Cell-cell communication influences detoxifying functions in hepatocytes"],"author":["Andreas Dr\u00e4ger","Daniel C Zielinski","Roland Keller","Matthias Rall","Johannes Eichner","Bernhard O Palsson","Andreas Zell"],"published_year":[2015],"organism":"(Missing value)","tag":["ODE","Modular rate law","kinetic model","modeling software","SBMLsqueezer","VLN"]},{"id":"Publication504","label":"Publication504","display_content":"","type":"Publication","item_id":504,"project":["D1: Regulation of Blood Flow and Perfusion in the Liver","D4: Regeneration and Liver Size","E3: Horizontal integration on organ scale","E4: Vertical integration across biological scales"],"author":["Constanze S\u00e4nger","Andrea Schenk","Lars Ole Schwen","Lei Wang","Felix Gremse","Sara Zafarnia","Fabian Kiessling","Chichi Xie","Weiwei Wei","Beate Richter","Olaf Dirsch","Uta Dahmen"],"published_year":[2015],"organism":"(Missing value)","tag":"(Missing value)"},{"id":"Publication487","label":"Publication487","display_content":"","type":"Publication","item_id":487,"project":["A1: Cellular metabolism","A2: Integration of Signalling Pathways in Hepatocellular Response","A3: Crosslinking signalling metabolism and hepatocyte polarisation","B: Communication of Hepatocytes and Non-Parenchymal Liver Cells","C: Liver lobule level","D: Whole organ level"],"author":["K. Abshagen","Matthias K\u00f6nig","Andreas Hoppe","I. Muller","M. Ebert","H. Weng","Hermann-Georg Holzh\u00fctter","Ulrich Zanger","Johannes Bode","B. Vollmar","Maria Thomas","Steven Dooley"],"published_year":[2015],"organism":"(Missing value)","tag":["Fluidigm","kinetic data","BDL","Bile duct ligation","cholestasis","VLN"]},{"id":"Publication501","label":"Publication501","display_content":"","type":"Publication","item_id":501,"project":["A1.2: Detoxification in hepatocytes challenged by steatotic conditions"],"author":["J. Zhang","U. Doshi","A. Suzuki","C. W. Chang","J\u00fcrgen Borlak","A. P. Li","W. Tong"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication480","label":"Publication480","display_content":"","type":"Publication","item_id":480,"project":["C6: Organization and function of the sinusoidal system and the liver lobule during regeneration after partial hepatectomy"],"author":["Bruno Christ","Sandra Br\u00fcckner","S. Winkler"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication498","label":"Publication498","display_content":"","type":"Publication","item_id":498,"project":["A1.3: Identification of crucial metabolic processes during hepatocyte proliferation","A3.2: Cross-talk of signaling pathways and endocytic machinery in hepatocytes: Impact on cell polarity and presence of transporters","A3.5: The impact of cell polarity on metabolism detoxification and endocytosis","C2: Organization of the sinusoidal system and the liver lobule - reference state","C5: Structural changes and functional consequences of the liver lobular/sinusoidal system during inflammation and fibrosis","C6: Organization and function of the sinusoidal system and the liver lobule during regeneration after partial hepatectomy"],"author":["Marius Garmhausen","Ute Hofmann","V. Senderov","Maria Thomas","B. A. Kandel","Bianca Habermann"],"published_year":[2015],"organism":"(Missing value)","tag":"(Missing value)"},{"id":"Publication488","label":"Publication488","display_content":"","type":"Publication","item_id":488,"project":["C3: Zonation of metabolism and its regulation"],"author":["M. Bartl","Michael Pfaff","A. Ghallab","Dominik Driesch","Sebastian Henkel","J. G. Hengstler","Stefan Schuster","C. Kaleta","Rolf Gebhardt","S. Zellmer","P. Li"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication497","label":"Publication497","display_content":"","type":"Publication","item_id":497,"project":["G2: Clinical Translation to Non-Invasive Volunteer Setting","G3: Clinical Translation to Pharmaceutical Drug Development"],"author":["M. G. Mooij","A. T. Nies","C. A. Knibbe","E. Schaeffeler","D. Tibboel","Matthias Schwab","S. N. de Wildt"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication489","label":"Publication489","display_content":"","type":"Publication","item_id":489,"project":["A3.6: Transcription factor network and links to metabolism in NAFLD"],"author":["H. Stark","M. Fichtner","R. Konig","S. Lorkowski","Stefan Schuster"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication494","label":"Publication494","display_content":"","type":"Publication","item_id":494,"project":["G2: Clinical Translation to Non-Invasive Volunteer Setting","G3: Clinical Translation to Pharmaceutical Drug Development"],"author":["J. Matthaei","J. Brockmoller","M. V. Tzvetkov","D. Sehrt","C. Sachse-Seeboth","J. B. Hjelmborg","S. Moller","U. Halekoh","Ute Hofmann","Matthias Schwab","Reinhold Kerb"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication491","label":"Publication491","display_content":"","type":"Publication","item_id":491,"project":["F1: The data management system","Virtual Liver"],"author":["F. Schreiber","G. D. Bader","Martin Golebiewski","M. Hucka","B. Kormeier","Nicolas Le Nov\u00e8re","C. Myers","D. Nickerson","B. Sommer","D. Waltemath","S. Weise"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication471","label":"Publication471","display_content":"","type":"Publication","item_id":471,"project":["A1.2: Detoxification in hepatocytes challenged by steatotic conditions","A3.4: Linking signalling to metabolic functions","B5: Cell-cell communication influences detoxifying functions in hepatocytes","Showcase LPS and Inflammation"],"author":["Ronny Feuer","Sebastian Vlaic","Janine Arlt","Oliver Sawodny","Uta Dahmen","Ulrich Zanger","Maria Thomas"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication472","label":"Publication472","display_content":"","type":"Publication","item_id":472,"project":["A3.4: Linking signalling to metabolic functions","B5: Cell-cell communication influences detoxifying functions in hepatocytes"],"author":["A. Braeuning","Maria Thomas","Ute Hofmann","S. Vetter","E. Zeller","B. Petzuch","J. Johanning","W. Schroth","Thomas Weiss","Ulrich Zanger","M. Schwarz"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication481","label":"Publication481","display_content":"","type":"Publication","item_id":481,"project":["C6: Organization and function of the sinusoidal system and the liver lobule during regeneration after partial hepatectomy"],"author":["S. Winkler","M. Hempel","Sandra Br\u00fcckner","F. Mallek","A. Weise","T. Liehr","H. M. Tautenhahn","M. Bartels","Bruno Christ"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication474","label":"Publication474","display_content":"","type":"Publication","item_id":474,"project":["A3.2: Cross-talk of signaling pathways and endocytic machinery in hepatocytes: Impact on cell polarity and presence of transporters"],"author":["Michael Martinez","Neil J. Bruce","Julia Romanowska","Daria B. Kokh","Musa Ozboyaci","Xiaofeng Yu","Mehmet Ali \u00d6zt\u00fcrk","Stefan Richter","Rebecca Wade"],"published_year":[2015],"organism":"(Missing value)","tag":["Brownian dynamics","macromolecular association","protein flexibility","biomacromolecular diffusion","VLN"]},{"id":"Publication477","label":"Publication477","display_content":"","type":"Publication","item_id":477,"project":["A3.2: Cross-talk of signaling pathways and endocytic machinery in hepatocytes: Impact on cell polarity and presence of transporters"],"author":["Nadinath B. Nillegoda","Janine Kirstein","Anna Szlachcic","Mykhaylo Berynskyy","Antonia Stank","Florian Stengel","Kristin Arnsburg","Xuechao Gao","Annika Scior","Ruedi Aebersold","D. Lys Guilbride","Rebecca Wade","Richard I. Morimoto","Matthias P. Mayer","Bernd Bukau"],"published_year":[2015],"organism":"(Missing value)","tag":["simulation","Chaperones","VLN"]},{"id":"Publication495","label":"Publication495","display_content":"","type":"Publication","item_id":495,"project":["G2: Clinical Translation to Non-Invasive Volunteer Setting","G3: Clinical Translation to Pharmaceutical Drug Development"],"author":["A. Emami Riedmaier","O. Burk","B. A. van Eijck","E. Schaeffeler","K. Klein","S. Fehr","S. Biskup","S. Muller","S. Winter","Ulrich Zanger","Matthias Schwab","A. T. Nies"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication468","label":"Publication468","display_content":"","type":"Publication","item_id":468,"project":["C1: The role of blood flow in liver lobule function and morphology","D1: Regulation of Blood Flow and Perfusion in the Liver","E3: Horizontal integration on organ scale","E4: Vertical integration across biological scales"],"author":["Lars Ole Schwen","Arne Schenk","Clemens Kreutz","Jens Timmer","Mar\u00eda Matilde Bartolom\u00e9 Rodr\u00edguez","Lars K\u00fcpfer","Tobias Preusser"],"published_year":[2015],"organism":["Homo sapiens"],"tag":["VLN"]},{"id":"Publication469","label":"Publication469","display_content":"","type":"Publication","item_id":469,"project":["F1: The data management system","Virtual Liver"],"author":["K. Wolstencroft","S. Owen","O. Krebs","Quyen Nguyen","N. J. Stanford","Martin Golebiewski","Andreas Weidemann","Meik Bittkowski","Lihua An","D. Shockley","J. L. Snoep","Wolfgang M\u00fcller","C. Goble"],"published_year":[2015],"organism":"(Missing value)","tag":["data management","knowledgebase","seek","database","VLN"]},{"id":"Publication473","label":"Publication473","display_content":"","type":"Publication","item_id":473,"project":["A3.4: Linking signalling to metabolic functions","B5: Cell-cell communication influences detoxifying functions in hepatocytes"],"author":["Maria Thomas","C. Bayha","Kathrin Klein","S. Muller","Thomas Weiss","Matthias Schwab","Ulrich Zanger"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication476","label":"Publication476","display_content":"","type":"Publication","item_id":476,"project":["F3: Kinetic data handling"],"author":["Xiaofeng Yu","Michael Martinez","Annika L. Gable","Jonathan Fuller","Neil J. Bruce","Stefan Richter","Rebecca Wade"],"published_year":[2015],"organism":"(Missing value)","tag":["web server","Brownian dynamics","macromolecular association","VLN"]},{"id":"Publication466","label":"Publication466","display_content":"","type":"Publication","item_id":466,"project":"(Missing value)","author":["Endre T Somogyi","Jean-Marie Bouteiller","James A Glazier","Matthias K\u00f6nig","J Kyle Medley","Maciej H Swat","Herbert M Sauro"],"published_year":[2015],"organism":["Homo sapiens"],"tag":["VLN"]},{"id":"Publication462","label":"Publication462","display_content":"","type":"Publication","item_id":462,"project":["A3.4: Linking signalling to metabolic functions","B5: Cell-cell communication influences detoxifying functions in hepatocytes"],"author":["N. Rodriguez","A. Thomas","L. Watanabe","I. Y. Vazirabad","V. Kofia","H. F. Gomez","F. Mittag","J. Matthes","J. Rudolph","F. Wrzodek","E. Netz","A. Diamantikos","J. Eichner","Roland Keller","C. Wrzodek","S. Frohlich","N. E. Lewis","C. J. Myers","Nicolas Le Nov\u00e8re","B. O. Palsson","M. Hucka","Andreas Dr\u00e4ger"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN","data management","JSBML","Software","modelling software","modeling software"]},{"id":"Publication493","label":"Publication493","display_content":"","type":"Publication","item_id":493,"project":["G2: Clinical Translation to Non-Invasive Volunteer Setting","G3: Clinical Translation to Pharmaceutical Drug Development"],"author":["F. Malentacchi","I. Mancini","I. Brandslund","P. Vermeersch","Matthias Schwab","J. Marc","R. H. van Schaik","G. Siest","E. Theodorsson","M. Pazzagli","C. Di Resta"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication499","label":"Publication499","display_content":"","type":"Publication","item_id":499,"project":["A1.3: Identification of crucial metabolic processes during hepatocyte proliferation","A3.2: Cross-talk of signaling pathways and endocytic machinery in hepatocytes: Impact on cell polarity and presence of transporters","A3.5: The impact of cell polarity on metabolism detoxification and endocytosis","C2: Organization of the sinusoidal system and the liver lobule - reference state","C5: Structural changes and functional consequences of the liver lobular/sinusoidal system during inflammation and fibrosis","C6: Organization and function of the sinusoidal system and the liver lobule during regeneration after partial hepatectomy"],"author":["Jose Villaveces","P. Koti","Bianca Habermann"],"published_year":[2015],"organism":"(Missing value)","tag":"(Missing value)"},{"id":"Publication463","label":"Publication463","display_content":"","type":"Publication","item_id":463,"project":["D4: Regeneration and Liver Size","Showcase Steatosis"],"author":["Andr\u00e9 Homeyer","Andrea Schenk","Janine Arlt","Uta Dahmen","Olaf Dirsch","Horst K. Hahn"],"published_year":[2015],"organism":"(Missing value)","tag":["steatosis","imageanalysis","VLN"]},{"id":"Publication458","label":"Publication458","display_content":"","type":"Publication","item_id":458,"project":["A2.2: Regulation of pro-apoptotic and anti-apoptotic responses in hepatocytes","A3.3: Hepatocyte polarity"],"author":["Christoph Meyer","Roman Liebe","Katja Breitkopf-Heinlein","Yan Liu","Alexandra M\u00fcller","Pia Rakoczy","Maria Thomas","Honglei Weng","Anastasia Bachmann","Matthias Ebert","Steven Dooley"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication475","label":"Publication475","display_content":"","type":"Publication","item_id":475,"project":["F3: Kinetic data handling"],"author":["Julia Romanowska","Daria B. Kokh","Jonathan Fuller","Rebecca Wade"],"published_year":[2015],"organism":"(Missing value)","tag":["drug-binding kinetics","macromolecular receptor","VLN"]},{"id":"Publication453","label":"Publication453","display_content":"","type":"Publication","item_id":453,"project":["A1.2: Detoxification in hepatocytes challenged by steatotic conditions","A3.6: Transcription factor network and links to metabolism in NAFLD"],"author":["Minjun Chen","Ayako Suzuki","J\u00fcrgen Borlak","Ra\u00fal J Andrade","M Isabel Lucena"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication455","label":"Publication455","display_content":"","type":"Publication","item_id":455,"project":["A2: Integration of Signalling Pathways in Hepatocellular Response","A2.1: Multi-level regulation of signalling pathways important for priming of hepatocyte proliferation and inflammatory response","A2.3: Cross-talk and distinct properties of growth factor signalling regulating cell-cycle progression and migration in hepatocytes","A2.4: Linking signalling pathways regulating liver regeneration and organ-size control","A3.2: Cross-talk of signaling pathways and endocytic machinery in hepatocytes: Impact on cell polarity and presence of transporters","A3.4: Linking signalling to metabolic functions","E1: Integration on the cellular level","Showcase HGF and Regeneration"],"author":["Lorenza D'Alessandro","Regina Samaga","Thomas Maiwald","Seong-Hwan Rho","Sandra Bonefas","Andreas Raue","Nao Iwamoto","Alexandra Kienast","Katharina Waldow","Ren\u00e9 Meyer","Marcel Schilling","Jens Timmer","Steffen Klamt","Ursula Klingm\u00fcller"],"published_year":[2015],"organism":["Mus musculus"],"tag":["VLN"]},{"id":"Publication454","label":"Publication454","display_content":"","type":"Publication","item_id":454,"project":["A3.6: Transcription factor network and links to metabolism in NAFLD"],"author":["J\u00fcrgen Borlak","Prafull Kumar Singh","Ina Rittelmeyer"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication492","label":"Publication492","display_content":"","type":"Publication","item_id":492,"project":["G2: Clinical Translation to Non-Invasive Volunteer Setting","G3: Clinical Translation to Pharmaceutical Drug Development"],"author":["R. Arlanov","T. Lang","G. Jedlitschky","E. Schaeffeler","T. Ishikawa","Matthias Schwab","A. T. Nies"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication496","label":"Publication496","display_content":"","type":"Publication","item_id":496,"project":["G2: Clinical Translation to Non-Invasive Volunteer Setting","G3: Clinical Translation to Pharmaceutical Drug Development"],"author":["S. Wolking","E. Schaeffeler","H. Lerche","Matthias Schwab","A. T. Nies"],"published_year":[2015],"organism":"(Missing value)","tag":["VLN"]},{"id":"Publication445","label":"Publication445","display_content":"","type":"Publication","item_id":445,"project":["A3.4: Linking signalling to metabolic functions","B5: Cell-cell communication influences detoxifying functions in hepatocytes","Showcase Steatosis"],"author":["Maria Thomas","Christine Bayha","Silvia Vetter","Ute Hofmann","Michael Schwarz","Ulrich Zanger","Albert Braeuning"],"published_year":[2015],"organism":"(Missing value)","tag":["PPARalpha","HepaRG cells","Wnt","drug metabolism","cytochrome P450","PXR","CAR","VLN"]},{"id":"Publication452","label":"Publication452","display_content":"","type":"Publication","item_id":452,"project":["A3.3: Hepatocyte polarity","A3.5: The impact of cell polarity on metabolism detoxification and endocytosis","Showcase LIAM (Liver Image Analysis Based Model)"],"author":["Osvaldo Chara","Lutz Brusch"],"published_year":[2015],"organism":"(Missing value)","tag":["hepatocyte volume regulation","bile secretion","VLN"]},{"id":"Publication490","label":"Publication490","display_content":"","type":"Publication","item_id":490,"project":["C6: Organization and function of the sinusoidal system and the liver lobule during regeneration after partial hepatectomy"],"author":["Stefan Ohrnberger","Abhishek Thavamani","Albert Braeuning","Daniel B. 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